Botanical species · safety record

Eleutherococcus sessiliflorus

The EFSA Compendium of Botanicals holds 17 constituent measurements and 2 adverse-effect records for Eleutherococcus sessiliflorus. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Eleutherococcus sessiliflorus (Rupr. & Maxim.) S.Y.Hu

17Constituent measurements

2Safety records

6Cited sources

0Licensed products (Canada)

Also recorded as

Acanthopanax sessiliflorus (Rupr. & Maxim.) Seem.

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Acanthoside b	Fruit unspecified	Solvent extraction	≥ 95.6 Microgram/gram	HPLC-UV	Resolve DOI
Acanthoside b	Fruit unspecified	Solvent extraction	≤ 180.8 Microgram/gram	HPLC-UV	Resolve DOI
Asarinin	Fruit unspecified	Solvent extraction	—	Chromatographic tests	Resolve DOI
Asarinin	Roots and other underground parts	Solvent extraction	—	LC-MS/MS	Resolve DOI
Chiisanoside	Leaves	Solvent extraction	4.1 Percent	Chromatographic tests	Resolve DOI
Helioxanthin	Roots and other underground parts	Solvent extraction	—	LC-MS/MS	Resolve DOI
Hydroxymethylfurfural	Fruit unspecified	Solvent extraction	—	Chromatographic tests	Resolve DOI
Liriodendrin	Fruit unspecified	Solvent extraction	—	Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)	Resolve DOI
Liriodendrin	Fruit unspecified	Solvent extraction	≥ 105.6 Microgram/gram	HPLC-UV	Resolve DOI
Liriodendrin	Fruit unspecified	Solvent extraction	≤ 211 Microgram/gram	HPLC-UV	Resolve DOI
Saponins	Leaves	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Savinin	Roots and other underground parts	Solvent extraction	—	LC-MS/MS	Resolve DOI
Scoparone	Fruit unspecified	Solvent extraction	—	Chromatographic tests	Resolve DOI
Scopolin	Fruit unspecified	Solvent extraction	143.4 Microgram/gram	HPLC-UV	Resolve DOI
Acanthoside b	Roots and other underground parts	Solvent extraction	0.62 Milligram/gram	Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)	No resolvable identifier
Eleutheroside b	Roots and other underground parts	Solvent extraction	0.55 Milligram/gram	Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)	No resolvable identifier
Liriodendrin	Roots and other underground parts	Solvent extraction	1.05 Milligram/gram	Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Digestive	Digestive: pancreas	Leaves	Solvent extraction	—	In vitro	Resolve DOI
Digestive	Digestive: pancreas	—	—	—	In vitro	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Yoshizumi, K., Hirano, K., Ando, H., Hirai, Y., Ida, Y., Tsuji, T., Tanaka, T., Satouchi, K., Terao, J. Lupane-type saponins from leaves of Acanthopanax sessiliflorus and their inhibitory activity on pancreatic lipase. Journal of Agricultural and Food Chemistry, 2006, vol. 54, no. 2, p. 335-341. DOI
Zhao, L., An, Q., Qin, F., Xiong, Z. Short Communication: Simultaneous determination of six constituents in the fruit of Acanthopanax sessiliflorus (Rupr. et Maxim.) Seem. by HPLC-UV. Natural Product Research, 2014, vol. 28, no. 7, p. 500-502. DOI
Ciesla, Lukasz., Zaluski, Daniel., Smolarz, Helena D., Hajnos, Michal., Waksmundzka-Hajnos, Monika. HPTLC-Densitometric Method for Determination of Eleutherosides B, E, and E1 in Different Eleutherococcus Species. Journal of Chromatographic Science, 2011, p. 182-188.
Lee, S., Ji, J., Shin, K.H., Kim, B.-K. Sessiline, a new nitrogenous compound from the fruits of Acanthopanax sessiliflorus. Planta Medica, 2002, vol. 68, no. 10, p. 939-941. DOI
Zaluski, Daniel., Smolarz, Helena Danuta., Szpilewska, Monika. Eleutherosides in Aerial Parts of Eleutherococcus Species Cultivated in Poland. JOURNAL OF AOAC INTERNATIONAL, 2011, vol. 94, no. 5, p. 1422-1426. DOI
Song, Y., Deng, Y., Huang, D., Wen, J., Liu, Z., Li, F. LC-MS/MS determination and pharmacokinetic study of four lignan components in rat plasma after oral administration of Acanthopanax sessiliflorus extract. Journal of Ethnopharmacology, 2012, vol. 141, no. 3, p. 957-963. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

Continue

Independent literature