Botanical species · safety record

Embelia ribes

The EFSA Compendium of Botanicals holds 11 constituent measurements and 8 adverse-effect records for Embelia ribes. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Embelia ribes Burm.f.

11Constituent measurements

8Safety records

8Cited sources

24Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 24 licensed products naming Embelia ribes as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Source material stated

Dried fruit
Edible fruit part
Fruit
Fruit extract
Root bark
Seed

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Embelin	Seed	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Embelin	Fruit unspecified	Solvent extraction	—	HPLC with standard detection methods	Resolve DOI
Alkaloids	Fruit unspecified	Solvent extraction	—	Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)	No resolvable identifier
Alkaloids	Aerial part of plants	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Anthraquinones	Fruit unspecified	Solvent extraction	—	Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)	No resolvable identifier
Cardiac glycosides	Fruit unspecified	Solvent extraction	—	Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)	No resolvable identifier
Embelin	Live plants	Solvent extraction	—	HPLC with standard detection methods	No resolvable identifier
Embelin	Fruit unspecified	Solvent extraction	2.5 Percent	Mass Spectroscopy and hyphenated methods without chromatography	No resolvable identifier
Plumbagin	Live plants	Solvent extraction	—	HPLC with standard detection methods	No resolvable identifier
Proanthocyanidins (condensed tannins)	Fruit peel	Solvent extraction	7.5 Percent	Phytochemical screening	No resolvable identifier
Tannins	Fruit unspecified	Solvent extraction	—	Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Digestive	Digestive	Leaves	Solvent extraction	Saccharomyces cerevisiae (as organism)	In vitro	Resolve DOI
Digestive	Digestive	Leaves	Solvent extraction	Saccharomyces cerevisiae (as organism)	In vitro	Resolve DOI
Digestive	Digestive	Leaves	Solvent extraction	Saccharomyces cerevisiae (as organism)	In vitro	Resolve DOI
Digestive	Digestive	Leaves	Solvent extraction	Saccharomyces cerevisiae (as organism)	In vitro	Resolve DOI
Digestive	Digestive	Leaves	Solvent extraction	Saccharomyces cerevisiae (as organism)	In vitro	Resolve DOI
Digestive	Digestive	Leaves	Solvent extraction	Saccharomyces cerevisiae (as organism)	In vitro	Resolve DOI
Reproductive	—	Live plants	—	Rat (as animal)	Reproduction toxicity	Resolve DOI
Reproductive	—	Live plants	—	Rat (as animal)	Reproduction toxicity	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Singh, Dharmendra., Singh, Ruchi., Singh, Pahup., Gupta, Radhey S. Effects of Embelin on Lipid Peroxidation and Free Radical Scavenging Activity against Liver Damage in Rats . Basic & clinical pharmacology & toxicology, 2009, vol. 105, no. 4, p. 243-248. DOI
Gopinath, S., Muralidharan, S., Rajan, S., Danaphal, S. P. Simultaneous estimation of plumbagin and embelin by reverse phase-high performance liquid chromatographic method. Archives of applied science research, 2009, vol. 1, no. 1, p. 135-142.
Mali, S., Borges, R. M. Phenolics, fibre, alkaloids, saponins, and cyanogenic glycosides in a seasonal cloud forest in India. Biochemical systematics and ecology, 2003, vol. 31, no. 11, p. 1221-1246.
Saraf, A., Srilata Srinivas, K., Chaturvedi, A. Phytochemical and elemental profile of Embelia ribes Burn. F. Research journal of pharmaceutical, biological and chemical sciences, 2016, vol. 7, no. 4, p. 471-476.
Joy, Beena., Kumar, S. Nishanth., Soumya, M. S., Radhika, A. R., Vibin, M., Abraham, Annie. Embelin (2,5-dihydroxy-3-undecyl-p-benzoquinone): A bioactive molecule isolated from Embelia ribes as an effective photodynamic therapeutic candidate against tumor in vivo . Phytomedicine, 2014, vol. 21, no. 11, p. 1292-1297. DOI
Singh, Inder Pal., Bharate, Sandip B., Singh, Anubha., Bhutani, Kamlesh K. Fate of embelin in Pippalyadi Yoga, an Ayurvedic oral contraceptive: Structure of embelin-borax complex and evaluation of anti-fertility activity . Indian journal of chemistry section b-organic chemistry including medicinal chemistry, 2007, vol. 46, no. 2, p. 320-325.
Phu Hoang Dang., Nhan Trung Nguyen., Hai Xuan Nguyen., Luan Sao Nguyen., Le, Tho Huu., Truong Nhat Van Do., Van Can, Mao., Mai Thanh Thi Nguyen. alpha-Glucosidase inhibitors from the leaves of Embelia ribes. Fitoterapia, 2015, vol. 100, p. 201-207. DOI
Kumar, Dinesh., Kumar, Ajay., Prakash, Om. Potential antifertility agents from plants: A comprehensive review. JOURNAL OF ETHNOPHARMACOLOGY, 2012, vol. 140, no. 1, p. 1-32. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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