Botanical species · safety record
Erythrophleum suaveolens
The EFSA Compendium of Botanicals holds 8 constituent measurements, 4 adverse-effect records and 1 genotoxicity assay for Erythrophleum suaveolens. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Erythrophleum suaveolens (Guill. & Perr.) Brenan (Erythrophleum guineense G. Don)
Regulatory presence
No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.
What the records describe
Constituents measured
- Diterpene alkaloids5
- Cassaine1
- Saponins1
- Tannins1
Plant parts
- Bark8
- Leaves3
- Wood1
Preparations
- Solvent extraction11
- Drying (dehydration)1
Effect types
- Pulmonary and cardiac2
- Hepatotoxicity1
- Systemic1
Target tissues
- Heart2
- Liver1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Diterpene alkaloids | Bark | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Tannins | Wood | Solvent extraction | — | GC-MS | Resolve DOI |
| Cassaine | Bark | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Diterpene alkaloids | Bark | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Diterpene alkaloids | Bark | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | No resolvable identifier |
| Diterpene alkaloids | Bark | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Diterpene alkaloids | Bark | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | No resolvable identifier |
| Saponins | Bark | Solvent extraction | — | Unspecified | No resolvable identifier |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Pulmonary and cardiac | Heart | Leaves | Solvent extraction | Rabbit (as animal) | Acute toxicity | Resolve DOI |
| Pulmonary and cardiac | Heart | Leaves | Solvent extraction | Rabbit (as animal) | Subchronic | Resolve DOI |
| Hepatotoxicity | Liver | Bark | Solvent extraction | Rat (as animal) | Short-term toxicity | No resolvable identifier |
| Systemic | — | Leaves | Drying (dehydration) | Sheep (as animal) | Short-term toxicity | No resolvable identifier |
Genotoxicity testing
Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.
| Outcome | Endpoint | Test | Tested organism | Metabolic activation | Source |
|---|---|---|---|---|---|
| Positive | chromosome aberration | chromosome aberration assay | Rat (as animal) | Not applicable | Resolve DOI |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Friedrich-Fiechtl, J., Spiteller, G. Use of mass spectrum analysis for structure elucidation of alkaloids. X. New alkaloids from Erythrophleum guineense and about Muawin . . Chemische berichte, 1971, vol. 104, no. 11, p. 3335-48.
- Saha, Jean-Bosco Tchinda., Abia, Daouda., Dumarcay, Stephane., Ndikontar, Maurice Kor., Gerardin, Philippe., Noah, Joseph Ngamveng., Perrin, Dominique. Antioxidant activities, total phenolic contents and chemical compositions of extracts from four Cameroonian woods: Padouk (Pterocarpus soyauxii Taubb), tali (Erythrophleum suaveolens), moabi (Baillonella toxisperma), and movingui (Distemonanthus benthamianus) . Industrial crops and products, 2013, vol. 41, p. 71-77. DOI
- Sowemimo, A. A., Fakoya, F. A., Awopetu, I., Omobuwajo, O. R., Adesanya, S. A. Toxicity and mutagenic activity of some selected Nigerian plants. Journal of ethnopharmacology, 2007, vol. 113, no. 3, p. 427-432. DOI
- NWUDE, N., CHINEME, CN. INVESTIGATIONS INTO THE TOXICITY OF THE LEAVES OF ERYTHROPHLEUM-GUINEENSE DON IN SHEEP . Research in veterinary science, 1980, vol. 28, no. 1, p. 112-115.
- Ashun, E., Oladimeji-Salami, J., Lartey-Young, G., Appah, J.K.M. Ameliorative effects of tamarind on the toxicity of Erythrophleum suaveolens in rabbits. Toxicology and environmental health sciences, 2017, vol. 9, no. 3, p. 199-208. DOI
- CRONLUND, A. NEW ALKALOIDS FROM ERYTHROPHLEUM SPECIES. Planta medica, 1973, vol. 24, no. 4, p. 371-374.
- Lindwall, Olle., Sandberg, Finn., Thorsen, Rune., Norin, Torbjorn. Erythrophleguine, a new alkaloid from the bark of Erythrophleum guineense. Tetrahedron letters, 1965, vol. (47), p. 4203-8.
- Manfouo, RN., Lontsi, D., Ngounou, FN., Ngadjui, BT., Sondengam, BL. Erythrosuavine, a new diterpenic alkaloid from Erythrophleum suaveolens (Guill. & Perr.) Brenan . Bulletin of the chemical society of ethiopia, 2005, vol. 19, no. 1, p. 69-74.
- Akinpelu, B. A., Dare, C. A., Adebesin, F. I., Iwalewa, E. O., Oyedapo, O. O. Effect of stem-bark of Erythrophleum suaveolens (Guill. & Perri.) saponin on fresh water snail (Lanistes lybicus) tissues. African journal of environmental science and technology, 2012, vol. 6, no. 11, p. 446-451.
- THORELL, A., AGURELL, S., SANDBERG, F., NORIN, T. 3 NEW ALKALOIDS FROM BARK OF ERYTHROPHLEUM GUINEENSE G DON SYN E SUAVEOLENS (GUILL + PERR) BRENAN . Acta chemica scandinavica, 1968, vol. 22, no. 9, p. 2835-&. DOI
- Adisa, Rahmat Adetutu., Nwalioba, Cosmos U., Akujobi, Sylvia., Oribabor, Jude. Sub-Acute Administration of Ethanol Extracts of Erythrophloem suavolens Induced Hepatotoxicity and Oxidative Stress in Wistar Strain Albino Rats . Faseb journal, 2016, vol. 30.
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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