Botanical species · safety record
Eschscholzia californica
The EFSA Compendium of Botanicals holds 33 constituent measurements for Eschscholzia californica. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Eschscholzia californica Cham.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 247 licensed products naming Eschscholzia californica as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Extract types on licence
Source material stated
What the records describe
Constituents measured
- Alkaloids11
- Californidine4
- Isoquinoline alkaloids4
- Allocryptopine3
- Chelerythrine3
- Protopine3
- Sanguinarine3
- Reticuline2
Plant parts
- Aerial part of plants30
- Unspecified2
- Roots and other underground parts1
Preparations
- Solvent extraction18
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Alkaloids | Aerial part of plants | — | 5.68 Milligram/kilogram | Unspecified | Resolve DOI |
| Alkaloids | Aerial part of plants | Solvent extraction | ≤ 0.55 Percent | HPLC with standard detection methods | Resolve DOI |
| Alkaloids | Aerial part of plants | Solvent extraction | ≥ 0.03 Percent | HPLC with standard detection methods | Resolve DOI |
| Alkaloids | Aerial part of plants | Solvent extraction | ≤ 1.08 Percent | HPLC with standard detection methods | Resolve DOI |
| Alkaloids | Aerial part of plants | — | 8.7 Milligram/kilogram | Unspecified | Resolve DOI |
| Alkaloids | Aerial part of plants | Solvent extraction | ≥ 0.19 Percent | HPLC with standard detection methods | Resolve DOI |
| Alkaloids | Aerial part of plants | Solvent extraction | 0.01 Percent | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Alkaloids | Aerial part of plants | — | 0.41 Milligram/kilogram | Unspecified | Resolve DOI |
| Alkaloids | Roots and other underground parts | — | 1.6 Percent | Unspecified | Resolve DOI |
| Allocryptopine | Aerial part of plants | — | 0.012 Milligram/kilogram | Unspecified | Resolve DOI |
| Allocryptopine | Aerial part of plants | Solvent extraction | 0.04 Percent | HPLC with standard detection methods | Resolve DOI |
| Allocryptopine | Aerial part of plants | Solvent extraction | 0.02 Percent | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Californidine | Aerial part of plants | Solvent extraction | ≥ 0.11 Percent | HPLC with standard detection methods | Resolve DOI |
| Californidine | Aerial part of plants | Solvent extraction | ≤ 0.98 Percent | HPLC with standard detection methods | Resolve DOI |
| Californidine | Aerial part of plants | Solvent extraction | 0.3 Percent | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Californidine | Aerial part of plants | — | 12.5 Milligram/kilogram | Unspecified | Resolve DOI |
| Chelerythrine | Aerial part of plants | Solvent extraction | ≥ 0.02 Percent | HPLC with standard detection methods | Resolve DOI |
| Chelerythrine | Aerial part of plants | Solvent extraction | ≤ 0.07 Percent | HPLC with standard detection methods | Resolve DOI |
| Chelerythrine | Aerial part of plants | — | 0.068 Milligram/kilogram | Unspecified | Resolve DOI |
| Isoquinoline alkaloids | Aerial part of plants | — | — | — | Resolve DOI |
| Isoquinoline alkaloids | Aerial part of plants | — | — | — | Resolve DOI |
| Isoquinoline alkaloids | Aerial part of plants | — | — | — | Resolve DOI |
| Isoquinoline alkaloids | Aerial part of plants | — | — | — | Resolve DOI |
| Protopine | Aerial part of plants | — | 0.514 Milligram/kilogram | Unspecified | Resolve DOI |
| Protopine | Aerial part of plants | Solvent extraction | 0.003 Percent | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Protopine | Aerial part of plants | Solvent extraction | 0.01 Percent | HPLC with standard detection methods | Resolve DOI |
| Reticuline | Aerial part of plants | — | — | — | Resolve DOI |
| Reticuline | Aerial part of plants | — | 1.095 Milligram/kilogram | Unspecified | Resolve DOI |
| Sanguinarine | Aerial part of plants | — | 0.0191 Milligram/kilogram | Unspecified | Resolve DOI |
| Sanguinarine | Aerial part of plants | Solvent extraction | ≤ 0.11 Percent | HPLC with standard detection methods | Resolve DOI |
| Sanguinarine | Aerial part of plants | Solvent extraction | ≥ 0.02 Percent | HPLC with standard detection methods | Resolve DOI |
| Alkaloids | Unspecified | Solvent extraction | — | Unspecified | No resolvable identifier |
| Alkaloids | Unspecified | Solvent extraction | — | Unspecified | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Al-Snafi, Ali Esmail. ESCHSCHOLZIA CALIFORNICA: A PHYTOCHEMICAL AND PHARMACOLOGICAL - REVIEW. Indo american journal of pharmaceutical sciences, 2017, vol. 4, no. 2, p. 257-263. DOI
- Tome, Franca., Colombo, Maria Laura., Caldiroli, Luisa. A comparative investigation on alkaloid composition in different populations of Eschscholtzia californica Cham . Phytochemical analysis, 1999, vol. 10, no. 5, p. 264-267. DOI
- Schramm, Anja., Saxena, Priyanka., Chlebek, Jakub., Cahlikova, Lucie., Baburin, Igor., Hering, Steffen., Hamburger, Matthias. Natural Products as Potential Human Ether-A-Go-Go-Related Gene Channel Inhibitors - Screening of Plant-Derived Alkaloids . Planta medica, 2014, vol. 80, no. 8-9, p. 740-746. DOI
- Manda, Vamshi K., Ibrahim, Mohamed A., Dale, Olivia R., Kumarihamy, Mallika., Cutler, Stephen J., Khan, Ikhlas A., Walker, Larry A., Muhammad, Ilias., Khan, Shabana I. Modulation of CYPs, P-gp, and PXR by Eschscholzia californica (California Poppy) and Its Alkaloids . Planta medica, 2016, vol. 82, no. 6, p. 551-558. DOI
- Manske, Richard H. F., HiShin, Kju. The alkaloids of Papaveraceous plants. LIII. Eschscholzia californica. Canadian journal of chemistry, 1965, vol. 43, no. 8, p. 2180-2.
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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