Botanical species · safety record

Eschscholzia californica

The EFSA Compendium of Botanicals holds 33 constituent measurements for Eschscholzia californica. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Eschscholzia californica Cham.

33Constituent measurements
0Safety records
5Cited sources
248Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 248 licensed products naming Eschscholzia californica as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

  • Dry
  • Extract Type TBA
  • Fresh
  • solid

Source material stated

  • Aerial part with flowers
  • Aerial parts
  • Dried aerial part(s)
  • Dried aerial parts
  • Eschscholzia californica - flower
  • Flower
  • Flowering top(s)
  • Flowers and leaves

What the records describe

Constituents measured

  • Alkaloids11
  • Californidine4
  • Isoquinoline alkaloids4
  • Allocryptopine3
  • Chelerythrine3
  • Protopine3
  • Sanguinarine3
  • Reticuline2

Plant parts

  • Aerial part of plants30
  • Unspecified2
  • Roots and other underground parts1

Preparations

  • Solvent extraction18

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
AlkaloidsAerial part of plantsSolvent extraction≥ 0.03 PercentHPLC with standard detection methodsResolve DOI
AlkaloidsAerial part of plantsSolvent extraction≥ 0.19 PercentHPLC with standard detection methodsResolve DOI
AlkaloidsAerial part of plantsSolvent extraction≤ 0.55 PercentHPLC with standard detection methodsResolve DOI
AlkaloidsAerial part of plantsSolvent extraction≤ 1.08 PercentHPLC with standard detection methodsResolve DOI
AlkaloidsAerial part of plantsSolvent extraction0.01 PercentNuclear Magnetic Resonance (NMR)Resolve DOI
AlkaloidsAerial part of plants—0.41 Milligram/kilogramUnspecifiedResolve DOI
AlkaloidsRoots and other underground parts—1.6 PercentUnspecifiedResolve DOI
AlkaloidsAerial part of plants—5.68 Milligram/kilogramUnspecifiedResolve DOI
AlkaloidsAerial part of plants—8.7 Milligram/kilogramUnspecifiedResolve DOI
AllocryptopineAerial part of plantsSolvent extraction0.04 PercentHPLC with standard detection methodsResolve DOI
AllocryptopineAerial part of plantsSolvent extraction0.02 PercentNuclear Magnetic Resonance (NMR)Resolve DOI
AllocryptopineAerial part of plants—0.012 Milligram/kilogramUnspecifiedResolve DOI
CalifornidineAerial part of plantsSolvent extraction≥ 0.11 PercentHPLC with standard detection methodsResolve DOI
CalifornidineAerial part of plantsSolvent extraction≤ 0.98 PercentHPLC with standard detection methodsResolve DOI
CalifornidineAerial part of plantsSolvent extraction0.3 PercentNuclear Magnetic Resonance (NMR)Resolve DOI
CalifornidineAerial part of plants—12.5 Milligram/kilogramUnspecifiedResolve DOI
ChelerythrineAerial part of plantsSolvent extraction≥ 0.02 PercentHPLC with standard detection methodsResolve DOI
ChelerythrineAerial part of plantsSolvent extraction≤ 0.07 PercentHPLC with standard detection methodsResolve DOI
ChelerythrineAerial part of plants—0.068 Milligram/kilogramUnspecifiedResolve DOI
Isoquinoline alkaloidsAerial part of plants———Resolve DOI
Isoquinoline alkaloidsAerial part of plants———Resolve DOI
Isoquinoline alkaloidsAerial part of plants———Resolve DOI
Isoquinoline alkaloidsAerial part of plants———Resolve DOI
ProtopineAerial part of plantsSolvent extraction0.01 PercentHPLC with standard detection methodsResolve DOI
ProtopineAerial part of plantsSolvent extraction0.003 PercentNuclear Magnetic Resonance (NMR)Resolve DOI
ProtopineAerial part of plants—0.514 Milligram/kilogramUnspecifiedResolve DOI
ReticulineAerial part of plants———Resolve DOI
ReticulineAerial part of plants—1.095 Milligram/kilogramUnspecifiedResolve DOI
SanguinarineAerial part of plantsSolvent extraction≥ 0.02 PercentHPLC with standard detection methodsResolve DOI
SanguinarineAerial part of plantsSolvent extraction≤ 0.11 PercentHPLC with standard detection methodsResolve DOI
SanguinarineAerial part of plants—0.0191 Milligram/kilogramUnspecifiedResolve DOI
AlkaloidsUnspecifiedSolvent extraction—UnspecifiedNo resolvable identifier
AlkaloidsUnspecifiedSolvent extraction—UnspecifiedNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Schramm, Anja., Saxena, Priyanka., Chlebek, Jakub., Cahlikova, Lucie., Baburin, Igor., Hering, Steffen., Hamburger, Matthias. Natural Products as Potential Human Ether-A-Go-Go-Related Gene Channel Inhibitors - Screening of Plant-Derived Alkaloids . Planta medica, 2014, vol. 80, no. 8-9, p. 740-746. DOI
  2. Tome, Franca., Colombo, Maria Laura., Caldiroli, Luisa. A comparative investigation on alkaloid composition in different populations of Eschscholtzia californica Cham . Phytochemical analysis, 1999, vol. 10, no. 5, p. 264-267. DOI
  3. Manda, Vamshi K., Ibrahim, Mohamed A., Dale, Olivia R., Kumarihamy, Mallika., Cutler, Stephen J., Khan, Ikhlas A., Walker, Larry A., Muhammad, Ilias., Khan, Shabana I. Modulation of CYPs, P-gp, and PXR by Eschscholzia californica (California Poppy) and Its Alkaloids . Planta medica, 2016, vol. 82, no. 6, p. 551-558. DOI
  4. Manske, Richard H. F., HiShin, Kju. The alkaloids of Papaveraceous plants. LIII. Eschscholzia californica. Canadian journal of chemistry, 1965, vol. 43, no. 8, p. 2180-2.
  5. Al-Snafi, Ali Esmail. ESCHSCHOLZIA CALIFORNICA: A PHYTOCHEMICAL AND PHARMACOLOGICAL - REVIEW. Indo american journal of pharmaceutical sciences, 2017, vol. 4, no. 2, p. 257-263. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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