Botanical species · safety record

Eupatorium cannabinum

The EFSA Compendium of Botanicals holds 7 constituent measurements for Eupatorium cannabinum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Eupatorium cannabinum L.

7Constituent measurements

0Safety records

5Cited sources

3Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 3 licensed products naming Eupatorium cannabinum as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

Flowering herb
Fresh aerial parts, collected at flowering time
Herb

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Pyrrolizidine alkaloids	Aerial part of plants	Solvent extraction	—	GC-MS	Resolve DOI
Pyrrolizidine alkaloids	Pollen-related	Solvent extraction	—	HPLC with standard detection methods	Resolve DOI
Pyrrolizidine alkaloids	Roots and other underground parts	Solvent extraction	—	GC-MS	Resolve DOI
Eupatoriopicrin	Aerial part of plants	—	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Intermedine	Stem / stalk	Solvent extraction	2620 Nanogram/gram	UHPLC-MS-MS	No resolvable identifier
Lycopsamine	Stem / stalk	Solvent extraction	620 Nanogram/gram	UHPLC-MS-MS	No resolvable identifier
Thymoquinone	Aerial part of plants	Solvent extraction	8 Milligram/kilogram	HPLC with standard detection methods	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Hendriks, H., Balraadjsing, W., Huizing, H J., Bruins, A P. Investigation into the Presence of Pyrrolizidine Alkaloids in Eupatorium cannabinum by Means of Positive and Negative Ion Chemical Ionization GC-MS. . Planta medica, 1987, vol. 53, no. 5, p. 456-61. DOI
Woerdenberg, H.J., Malingre, T.M., Lemstra, W., Konings, A.W.T. Reduced levels of glutathione in liver and tumour tissue of the mouse after administration of eupatoriopicrin. Phytotherapy research, 1988, vol. 2, no. 2, p. 80-84.
Avula, Bharathi., Sagi, Satyanarayanaraju., Wang, Yan-Hong., Zweigenbaum, Jerry., Wang, Mei., Khan, Ikhlas A. Characterization and screening of pyrrolizidine alkaloids and N-oxides from botanicals and dietary supplements using UHPLC-high resolution mass spectrometry. Food Chemistry, 2015, p. 136-148.
Boppre, Michael., Colegate, Steven M., Edgar, John A., Fischer, Ottmar W. Hepatotoxic pyrrolizidine alkaloids in pollen and drying-related implications for commercial processing of bee pollen. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2008, vol. 56, no. 14, p. 5662-5672. DOI
Taborsky, Jan., Kunt, Miroslav., Kloucek, Pavel., Lachman, Jaromir., Zeleny, Vaclav., Kokoska, Ladislav. Identification of potential sources of thymoquinone and related compounds in Asteraceae, Cupressaceae, Lamiaceae, and Ranunculaceae families. Central European Journal of Chemistry, 2012, p. 1899-1906.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature