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Botanical species · safety record

Eupatorium perfoliatum

The EFSA Compendium of Botanicals holds 4 constituent measurements for Eupatorium perfoliatum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Eupatorium perfoliatum L.

4Constituent measurements
0Safety records
3Cited sources
122Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 122 licensed products naming Eupatorium perfoliatum as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

  • Aerial flowering part
  • Aerial part with flowers
  • Aerial parts
  • Flower
  • Flower buds
  • Flowering aerial part(s)
  • Flowering aerial parts
  • Flowering tops

What the records describe

Constituents measured

  • Sesquiterpene lactones2
  • Intermedine1
  • Lycopsamine1

Plant parts

  • Aerial part of plants2
  • Roots and other underground parts2

Preparations

  • Drying (dehydration)2
  • Solvent extraction2

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
Sesquiterpene lactonesAerial part of plantsSolvent extraction—High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
Sesquiterpene lactonesAerial part of plantsSolvent extraction—Nuclear Magnetic Resonance (NMR)Resolve DOI
IntermedineRoots and other underground partsDrying (dehydration)860 Nanogram/gramUHPLC-MS-MSNo resolvable identifier
LycopsamineRoots and other underground partsDrying (dehydration)3100 Nanogram/gramUHPLC-MS-MSNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Maas, Mareike., Hensel, Andreas., da Costa, Fernando Batista., Brun, Reto., Kaiser, Marcel., Schmidt, Thomas J. An unusual dimeric guaianolide with antiprotozoal activity and further sesquiterpene lactones from Eupatorium perfoliatum. PHYTOCHEMISTRY, 2011, vol. 72, no. 7, p. 635-644. DOI
  2. HERZ, W., KALYANARAMAN, PS., RAMAKRISHNAN, G., BLOUNT, JF. SESQUITERPENE LACTONES OF EUPATORIUM-PERFOLIATUM. JOURNAL OF ORGANIC CHEMISTRY, 1977, vol. 42, no. 13, p. 2264-2271. DOI
  3. Avula, Bharathi., Sagi, Satyanarayanaraju., Wang, Yan-Hong., Zweigenbaum, Jerry., Wang, Mei., Khan, Ikhlas A. Characterization and screening of pyrrolizidine alkaloids and N-oxides from botanicals and dietary supplements using UHPLC-high resolution mass spectrometry. Food Chemistry, 2015, p. 136-148.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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