Botanical species · safety record
Eupatorium purpureum
The EFSA Compendium of Botanicals holds 4 constituent measurements for Eupatorium purpureum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Eupatorium purpureum L.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 47 licensed products naming Eupatorium purpureum as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Extract types on licence
Source material stated
What the records describe
Constituents measured
- Benzofurans1
- Intermedine1
- Lycopsamine1
- Pyrrolizidine alkaloids1
Plant parts
- Roots and other underground parts3
- Seed1
Preparations
- Solvent extraction4
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Benzofurans | Roots and other underground parts | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Intermedine | Roots and other underground parts | Solvent extraction | 200 Nanogram/gram | LC-MS-MS (QqQ) | No resolvable identifier |
| Lycopsamine | Roots and other underground parts | Solvent extraction | 30 Nanogram/gram | LC-MS-MS (QqQ) | No resolvable identifier |
| Pyrrolizidine alkaloids | Seed | Solvent extraction | 4.65 Percent | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Avula, Bharathi., Sagi, Satyanarayanaraju., Wang, Yan-Hong., Zweigenbaum, Jerry., Wang, Mei., Khan, Ikhlas A. Characterization and screening of pyrrolizidine alkaloids and N-oxides from botanicals and dietary supplements using UHPLC-high resolution mass spectrometry. Food chemistry, 2015, vol. 178, p. 136-148.
- Habtemariam, S. Antiinflammatory activity of the antirheumatic herbal drug, gravel root (Eupatorium purpureum): Further biological activities and constituents . Phytotherapy research, 2001, vol. 15, no. 8, p. 687-690. DOI
- These, Anja., Bodi, Dorina., Ronczka, Stefan., Lahrssen-Wiederholt, Monika., Preiss-Weigert, Angelika. Structural screening by multiple reaction monitoring as a new approach for tandem mass spectrometry: presented for the determination of pyrrolizidine alkaloids in plants. Analytical and bioanalytical chemistry, 2013, vol. 405, no. 29, p. 9375-9383.
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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