Botanical species · safety record

Eupatorium purpureum

The EFSA Compendium of Botanicals holds 4 constituent measurements for Eupatorium purpureum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Eupatorium purpureum L.

4Constituent measurements
0Safety records
3Cited sources
47Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 47 licensed products naming Eupatorium purpureum as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

  • Dry
  • Extract Type TBA

Source material stated

  • Fresh underground parts collected after flowers have fallen off
  • Herb
  • Leaf
  • Root
  • Root and Rhizome

What the records describe

Constituents measured

  • Benzofurans1
  • Intermedine1
  • Lycopsamine1
  • Pyrrolizidine alkaloids1

Plant parts

  • Roots and other underground parts3
  • Seed1

Preparations

  • Solvent extraction4

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
BenzofuransRoots and other underground partsSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
IntermedineRoots and other underground partsSolvent extraction200 Nanogram/gramLC-MS-MS (QqQ)No resolvable identifier
LycopsamineRoots and other underground partsSolvent extraction30 Nanogram/gramLC-MS-MS (QqQ)No resolvable identifier
Pyrrolizidine alkaloidsSeedSolvent extraction4.65 PercentHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Avula, Bharathi., Sagi, Satyanarayanaraju., Wang, Yan-Hong., Zweigenbaum, Jerry., Wang, Mei., Khan, Ikhlas A. Characterization and screening of pyrrolizidine alkaloids and N-oxides from botanicals and dietary supplements using UHPLC-high resolution mass spectrometry. Food chemistry, 2015, vol. 178, p. 136-148.
  2. Habtemariam, S. Antiinflammatory activity of the antirheumatic herbal drug, gravel root (Eupatorium purpureum): Further biological activities and constituents . Phytotherapy research, 2001, vol. 15, no. 8, p. 687-690. DOI
  3. These, Anja., Bodi, Dorina., Ronczka, Stefan., Lahrssen-Wiederholt, Monika., Preiss-Weigert, Angelika. Structural screening by multiple reaction monitoring as a new approach for tandem mass spectrometry: presented for the determination of pyrrolizidine alkaloids in plants. Analytical and bioanalytical chemistry, 2013, vol. 405, no. 29, p. 9375-9383.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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