Botanical species · safety record

Euphorbia helioscopia

The EFSA Compendium of Botanicals holds 6 constituent measurements and 1 adverse-effect record for Euphorbia helioscopia. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Euphorbia helioscopia L.

6Constituent measurements

1Safety records

4Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Diterpene esters	Aerial part of plants	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Scoparone	Live plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Scopoletin	Live plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Alkaloids	Aerial part of plants	Solvent extraction	≥ 3.56 Percent	UV/VIS spectroscopy (photometry)	No resolvable identifier
Alkaloids	Aerial part of plants	Solvent extraction	≤ 41.84 Percent	UV/VIS spectroscopy (photometry)	No resolvable identifier
Saponin glycosides	Aerial part of plants	Solvent extraction	≤ 34 Percent	UV/VIS spectroscopy (photometry)	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Systemic	Heart	Aerial part of plants	Drying (dehydration)	Goat (as animal)	Short-term toxicity	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Geng, Di., Weng, Lianjin., Han, Yuanyuan., Yang, Xin., Wen, YX., Lei, FH. Chemical Constituents from Euphorbia helioscopia. Advances in chemical engineering, pts 1-3, 2012, vol. 396-398, p. 1337-1340. DOI
Saleem, Uzma., Hussain, Khalid., Ahmad, Mobasher., Bukhari, Nadeem Irfan., Malik, Arif., Ahmad, Bashir. Physicochemical and phytochemical analysis of Euphorbia helioscopia (L.). Pakistan journal of pharmaceutical sciences, 2014, vol. 27, no. 3, p. 577-585.
Zayed, SMAD., Farghaly, M., Taha, H., Gotta, H., Hecker, E. Dietary cancer risk conditional cancerogens in produce of livestock fed on species of spurge (Euphorbiaceae) - I. Skin irritant and tumor-promoting ingenane-type diterpene esters in E-peplus, one of several herbaceous Euphoria species contaminating fodder of livestock. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 1998, vol. 124, no. 3-4, p. 131-140. DOI
Nawito, M., Ahmed, YF., Shalaby, SI., Nada, A., Zayed, SMAD., Hecker, E. Dietary cancer risk from conditional cancerogens (tumor promoters) in produce of livestock fed on species of spurge (Euphorbiaceae) IV. Toxicologic and pathophysiologic observations in lactating goats and their suckling kids fed on the irritant herbs Euphorbia nubica and Euphorbia helioscopia: an etiologic model for investigations on the putative risk of cancer by consumption of food polluted with tumor promoters. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2001, vol. 127, no. 1, p. 34-39. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature