Botanical species · safety record

Excoecaria agallocha

The EFSA Compendium of Botanicals holds 21 constituent measurements for Excoecaria agallocha. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Excoecaria agallocha L.

21Constituent measurements

0Safety records

15Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Diterpenes	Roots and other underground parts	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Diterpenes	Roots and other underground parts	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Diterpenes	Roots and other underground parts	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Diterpenes	Wood	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Diterpenes	Wood	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Diterpenes	Wood	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Excoecarins	Stem / stalk	Solvent extraction	—	Mass Spectroscopy and hyphenated methods without chromatography	Resolve DOI
Excoecarins	Wood	—	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Labdane diterpenes	Wood	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Phorbol esters	Live plants	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Diterpenes	Stem / stalk	Solvent extraction	—	Mass Spectroscopy and hyphenated methods without chromatography	No resolvable identifier
Diterpenes	Wood	—	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Excoecarins	Wood	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	No resolvable identifier
Labdane diterpenes	Wood	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Pentacyclic triterpenic derivatives	—	—	—	—	No resolvable identifier
Pentacyclic triterpenic derivatives	Stem / stalk	—	—	—	No resolvable identifier
Pentacyclic triterpenic derivatives	Leaves	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	No resolvable identifier
Pentacyclic triterpenic derivatives	Stem / stalk	Solvent extraction	—	Mass Spectroscopy and hyphenated methods without chromatography	No resolvable identifier
Pentacyclic triterpenic derivatives	Leaves	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Pentacyclic triterpenic derivatives	Stem / stalk	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Tannins	Bark	—	10 Percent	—	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Li Xiang., Yao Yan-Hua., Zheng Yi-Nan., Lin Wen-Han., Deng Zhi-Wei. Chemical constituents of mangrove plant Excoecaria agallocha. Chinese journal of natural medicines, 2006, vol. 4, no. 3, p. 188-191.
Anjaneyulu, V., Babu, J. Suresh., Babu, B. Hari., Reddy, M. Venkata. Terpenoids from a mangrove, Excoecaria agallocha.. Acta ciencia indica, chemistry, 1993, vol. 19, no. 4, p. 123-6.
Hoque, Muzzammel. Utilization of bark tannins from Excoecaria agallocha Linn. Bangladesh journal of scientific and industrial research, 1982, vol. 17(1-2), p. 70-9.
Santhanam, Satyan Ramachandran., Subramanian, Malarvannan., Egigu, Meseret C., Parida, Ajay. Pentacyclic triterpenoids and a linear alkane from the milky mangrove tree (Excoecaria agallocha L.) are toxic to the larva of Helicoverpa armigera Hubner. (Lepidoptera: Noctuidae). International journal of advanced research, 2014, vol. 2, no. 6), 1-1, p. 12 pp.
Anjaneyulu, ASR., Rao, VL., Sreedhar, K. ent-kaurane and beyerane diterpenoids from Excoecaria agallocha. Journal of natural products, 2002, vol. 65, no. 3, p. 382-385. DOI
Konishi, T., Kiyosawa, S., Konoshima, T., Fujiwara, Y. Chemical structures of excoecarins A, B and C: Three new labdane-type diterpenes from wood, Excoecaria agallocha . Chemical & pharmaceutical bulletin, 1996, vol. 44, no. 11, p. 2100-2102.
Konishi, T., Konoshima, T., Fujiwara, Y., Kiyosawa, S. Excoecarins D, E, and K, from Excoecaria agallocha. Journal of natural products, 2000, vol. 63, no. 3, p. 344-346. DOI
Konishi, T., Yamazoe, K., Konoshima, T., Fujiwara, Y. Seco-labdane type diterpenes from Excoecaria agallocha. Phytochemistry, 2003, vol. 64, no. 4, p. 835-840. DOI
ERICKSON, KL., BEUTLER, JA., CARDELLINA, JH., MCMAHON, JB., NEWMAN, DJ., BOYD, MR. A NOVEL PHORBOL ESTER FROM EXCOECARIA-AGALLOCHA. Journal of natural products-lloydia, 1995, vol. 58, no. 5, p. 769-772. DOI
Liu, Zhen., Jiang, Wei., Deng, Zhi-Wei., Lin, Wen-Han. Assignment of the absolute stereochemistry of an unusual diterpenoid from the mangrove plant Excoecaria agallocha L. Journal of chinese pharmaceutical sciences, 2010, vol. 19, no. 5, p. 387-392.
Konishi, T., Yamazoe, K., Kanzato, M., Konoshima, T., Fujiwara, Y. Three diterpenoids (Excoecarins V1-V3) and a flavanone glycoside from the fresh stem of Excoecaria agallocha . Chemical & pharmaceutical bulletin, 2003, vol. 51, no. 10, p. 1142-1146. DOI
Konishi, T., Konoshima, T., Maoka, T., Fujiwara, Y. Novel diterpenes, excoecarins M and N from the resinous wood of Excoecaria agallocha . Tetrahedron letters, 2000, vol. 41, no. 18, p. 3419-3422. DOI
Konishi, T., Konoshima, T., Fujiwara, Y., Kiyosawa, S., Miyahara, K., Nishi, M. Stereostructures of new labdane-type diterpenes, excoecarins F, G1, and G2 from the wood of Excoecaria agallocha . Chemical & pharmaceutical bulletin, 1999, vol. 47, no. 3, p. 456-458.
Hui, W. H., Sung, M. L. An examination of the Euphorbiaceae of Hong Kong. II. The occurrence of epitaraxerol and other triterpenoids. Australian journal of chemistry, 1968, vol. 21, no. 8, p. 2137-40.
Konishi, T., Takasaki, M., Tokuda, H., Kiyosawa, S., Konoshima, T. Anti-tumor-promoting activity of diterpenes from Excoecaria agallocha. Biological & pharmaceutical bulletin, 1998, vol. 21, no. 9, p. 993-996.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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