Botanical species · safety record

Ferula assa-foetida

The EFSA Compendium of Botanicals holds 6 constituent measurements and 2 adverse-effect records for Ferula assa-foetida. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Ferula assa-foetida L.

6Constituent measurements

2Safety records

4Cited sources

8Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 8 licensed products naming Ferula assa-foetida as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

Ferula assa-foetida - gum oleoresin
Flower
Gum oleoresin
Root extract

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Conferone	Roots and other underground parts	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	No resolvable identifier
Coumarins	Live plants	Solvent extraction	—	Chromatographic tests	No resolvable identifier
Coumarins	Live plants	Solvent extraction	—	Chromatographic tests	No resolvable identifier
Coumarins	Roots and other underground parts	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	No resolvable identifier
Gummosin	—	—	—	—	No resolvable identifier
Umbelliprenin	Roots and other underground parts	—	—	—	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Hepatotoxicity	Liver	—	Oleo-gum-resin (as part-nature)	Rat (as animal)	Short-term toxicity	Resolve DOI
Nephrotoxicity	Urogenital: kidneys	—	Oleo-gum-resin (as part-nature)	Rat (as animal)	Short-term toxicity	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Goudah, A., Abo-El-Sooud, K., Yousef, M.A. Acute and subchronic toxicity assessment model of Ferula assa-foetida gum in rodents. Veterinary World, 2015, vol. 8, no. 5, p. 584-589. DOI
Asghari J., Atabaki V., Baher E., Mazaheritehrani M. Identification of sesquiterpene coumarins of oleo-gum resin of Ferula assa-foetida L. from the Yasuj region. Natural product research, 2015, p. 1-4.
Nassar, M. I., Abu-Mustafa, E. A., Ahmed, A. A. Sesquiterpene coumarins from Ferula assafoetida L. Pharmazie, 1995, p. 766-767.
Banerji, A., Mallick, B., Chatterjee, A., Budzikiewicz, H., Breuer, M. Assafoetidin and ferocolicin, two sesquiterpenoid coumarins from Ferula assafoetida Regel. Tetrahedron Letters, 1988, p. 1557-1560.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature