Botanical species · safety record

Fumaria officinalis

The EFSA Compendium of Botanicals holds 67 constituent measurements for Fumaria officinalis. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Fumaria officinalis L.

67Constituent measurements

0Safety records

6Cited sources

60Licensed products (Canada)

Also recorded as

Fumaria officinalis subsp. officinalis

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 60 licensed products naming Fumaria officinalis as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Source material stated

Aerial parts
Flower
Flowering aerial part(s)
Flowering aerial plant
Flowering top(s)
Fresh aerial part
Fresh aerial part collected at flowering time
Fresh aerial parts collected at flowering time

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
3,4-dihydroxybenzoic acid	Aerial part of plants	Solvent extraction	—	GC-MS	Resolve DOI
Adlumine	Aerial part of plants	Solvent extraction	2 Percent	GC-MS	Resolve DOI
Alkaloids	Aerial part of plants	Solvent extraction	540 Milligram/100 gram	GC-MS	Resolve DOI
Chelidonine	Unspecified	Solvent extraction	650 Microgram/gram	Mass Spectroscopy and hyphenated methods without chromatography	Resolve DOI
Coptisine	Aerial part of plants	Solvent extraction	≤ 0.9 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Coptisine	Aerial part of plants	Solvent extraction	≥ 0.3 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Corytuberine	Aerial part of plants	Solvent extraction	≤ 2.6 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Corytuberine	Aerial part of plants	Solvent extraction	≥ 0.6 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Cryptopine	Aerial part of plants	Solvent extraction	≤ 7.3 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Cryptopine	Aerial part of plants	Solvent extraction	≥ 2.8 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Cryptopine	Aerial part of plants	Solvent extraction	11 Percent	GC-MS	Resolve DOI
Cryptopine	Aerial part of plants	Solvent extraction	9.9 Percent	GC-MS	Resolve DOI
Dihydrosanguinarine	Aerial part of plants	Solvent extraction	< 2 Percent	GC-MS	Resolve DOI
Fumarilin	Aerial part of plants	Solvent extraction	2.5 Percent	GC-MS	Resolve DOI
Fumarilin	Aerial part of plants	Solvent extraction	≤ 3.9 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Fumarilin	Aerial part of plants	Solvent extraction	≥ 2 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Fumarilin	Aerial part of plants	Solvent extraction	3 Percent	GC-MS	Resolve DOI
Fumarilin	Aerial part of plants	Solvent extraction	7.3 Percent	GC-MS	Resolve DOI
Fumaritine	Aerial part of plants	Solvent extraction	≤ 3.4 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Fumaritine	Aerial part of plants	Solvent extraction	≥ 2.7 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Fumaritine	Aerial part of plants	Solvent extraction	6 Percent	GC-MS	Resolve DOI
Fumaritine	Aerial part of plants	Solvent extraction	6.8 Percent	GC-MS	Resolve DOI
Fumarophycine	Aerial part of plants	Solvent extraction	≤ 29.8 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Fumarophycine	Aerial part of plants	Solvent extraction	≥ 17.1 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Fumarophycine	Aerial part of plants	Solvent extraction	≤ 37.4 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Fumarophycine	Aerial part of plants	Solvent extraction	≥ 19.3 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Fumarophycine	Aerial part of plants	Solvent extraction	24 Percent	GC-MS	Resolve DOI
Fumarophycine	Aerial part of plants	Solvent extraction	10.3 Percent	GC-MS	Resolve DOI
Isoquinoline alkaloids	Aerial part of plants	Solvent extraction	≥ 624.4 Milligram/100 gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Isoquinoline alkaloids	Aerial part of plants	Solvent extraction	≤ 1386.1 Milligram/100 gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Isoquinoline alkaloids	Aerial part of plants	Solvent extraction	1.9 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Isoquinoline alkaloids	Unspecified	Solvent extraction	—	Mass Spectroscopy and hyphenated methods without chromatography	Resolve DOI
Isoquinoline alkaloids	Aerial part of plants	Solvent extraction	≤ 3 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Isoquinoline alkaloids	Aerial part of plants	Solvent extraction	0.8 Percent	GC-MS	Resolve DOI
P-coumaric acid	Aerial part of plants	Solvent extraction	—	GC-MS	Resolve DOI
Parfumine	Aerial part of plants	Solvent extraction	10.1 Percent	GC-MS	Resolve DOI
Parfumine	Aerial part of plants	Solvent extraction	≤ 5.4 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Parfumine	Aerial part of plants	Solvent extraction	≥ 4 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Parfumine	Aerial part of plants	Solvent extraction	3 Percent	GC-MS	Resolve DOI
Protopine	Unspecified	Solvent extraction	3726.6 Microgram/gram	Mass Spectroscopy and hyphenated methods without chromatography	Resolve DOI

40 of 67 records are shown, ordered so that records carrying a resolvable reference come first.

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Sousek, J., Guedon, D., Adam, T., Bochorakova, H., Taborska, E., Valka, I., Simanek, V. Alkaloids and organic acids content of eight Fumaria species. PHYTOCHEMICAL ANALYSIS, 1999, vol. 10, no. 1, p. 6-11. DOI
Paltinean, Ramona., Toiu, Anca., Wauters, Jean Noel., Frederich, Michel., Tits, Monique., Angenot, Luc., Tamas, Mircea., Crisan, Gianina. PHYTOCHEMICAL ANALYSIS OF FUMARIA OFFICINALIS L. (FUMARIACEAE). Farmacia, 2016, vol. 64, no. 3, p. 409-413.
Suau, R., Cabezudo, B., Rico, R., Najera, F., Lopez-Romero, JM. Direct determination of alkaloid contents in Fumaria species by GC-MS. Phytochemical analysis, 2002, vol. 13, no. 6, p. 363-367. DOI
Vrancheva, Radka Z., Ivanov, Ivan G., Aneva, Ina Y., Dincheva, Ivayla N., Badjakov, Ilian K., Pavlov, Atanas I. Alkaloid profiles and acetylcholinesterase inhibitory activities of Fumaria species from Bulgaria . Zeitschrift fur naturforschung section c-a journal of biosciences, 2016, vol. 71, no. 1-2, p. 9-14. DOI
Och, Anna., Szewczyk, Katarzyna., Pecio, Lukasz., Stochmal, Anna., Zaluski, Daniel., Bogucka-Kocka, Anna. UPLC-MS/MS Profile of Alkaloids with Cytotoxic Properties of Selected Medicinal Plants of the Berberidaceae and Papaveraceae Families. . Oxidative medicine and cellular longevity, 2017, vol. 2017, p. 9369872-9369872. DOI
Sharma, Uday Raj., Surendra, V., Goli, Divakar. Evaluation of Analgesic activity of Ethanolic extracts of Fumaria officinalis Linn. in experimental animals. Journal of fundamental pharmaceutical research, 2014, vol. 2, no. 1, p. 49-56.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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