Botanical species · safety record

Galega officinalis

The EFSA Compendium of Botanicals holds 17 constituent measurements and 3 adverse-effect records for Galega officinalis. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Galega officinalis L.

17Constituent measurements

3Safety records

9Cited sources

30Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 30 licensed products naming Galega officinalis as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Source material stated

Aerial parts
Grass(es)
Herb
Herb top
Herb(s)
Leaf
Whole plant
Whole plant(s)

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Galegine	Stem / stalk	Solvent extraction	≥ 1.27 Milligram/gram	LC-MS	Resolve DOI
Galegine	Stem / stalk	Solvent extraction	≥ 2.8 Milligram/gram	LC-MS	Resolve DOI
Galegine	Stem / stalk	Solvent extraction	≤ 1.85 Milligram/gram	LC-MS	Resolve DOI
Galegine	Stem / stalk	Solvent extraction	≤ 6.22 Milligram/gram	LC-MS	Resolve DOI
Alkaloids	Aerial part of plants	Solvent extraction	—	UHPLC-MS-MS	No resolvable identifier
Alkaloids	Aerial part of plants	Solvent extraction	—	UHPLC-MS-MS	No resolvable identifier
Alkaloids	Aerial part of plants	—	—	—	No resolvable identifier
Alkaloids	Unspecified	Solvent extraction	—	—	No resolvable identifier
Benzophenanthridine alkaloids	Aerial part of plants	Solvent extraction	—	UHPLC-MS-MS	No resolvable identifier
Cardiac glycosides	Unspecified	Solvent extraction	—	—	No resolvable identifier
Galegine	Seed	Solvent extraction	—	—	No resolvable identifier
Galegine	Aerial part of plants	—	—	—	No resolvable identifier
Isoquinoline	Aerial part of plants	Solvent extraction	—	UHPLC-MS-MS	No resolvable identifier
Peganine	Aerial part of plants	—	—	—	No resolvable identifier
Quinoline alkaloids	Aerial part of plants	Solvent extraction	—	UHPLC-MS-MS	No resolvable identifier
Saponins	Unspecified	Solvent extraction	—	—	No resolvable identifier
Tannins	Unspecified	Solvent extraction	—	—	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Hepatotoxicity	Lung	Aerial part of plants	—	Rat (as animal)	Subchronic	Resolve DOI
Pulmonary and cardiac	Respiratory	Aerial part of plants	Drying (dehydration)	Sheep (as animal)	Case report	No resolvable identifier
Pulmonary and cardiac	Respiratory	Aerial part of plants	Drying (dehydration)	Cattle (as animal)	Case report	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Nardin, Tiziana., Piasentier, Edi., Barnaba, Chiara., Larcher, Roberto. Alkaloid profiling of herbal drugs using high resolution mass spectrometry. Drug testing and analysis, 2017, p. Ahead of Print.
Oldham, Michelle., Ransom, Corey V., Ralphs, Michael H., Gardner, Dale R. Galegine Content in Goatsrue (Galega officinalis) Varies by Plant Part and Phenological Growth Stage . Weed science, 2011, vol. 59, no. 3, p. 349-352. DOI
Barger, Geo., White, F. D. Constitution of galegine. Biochemical journal, 1923, vol. 17, p. 827-35.
Luka, C. D., Omoniwa, B. P. Effect of some phytochemicals extracted from Goat's rue (Galega officinalis) on some biochemical parameters in normal and alloxan-induced diabetic rats. Journal of natural product and plant resources, 2012, vol. 2, no. 5, p. 628-632.
Fraiture, A. Toxicity to livestock and medicinal uses of Galega officinalis (Leguminosae) and galegine Toxicit� pour le b�tail et usages m�dicinaux du Galega officinalis (Leguminosae) et de la gal�gine . Annales de medecine veterinaire, 2014, vol. 158, no. 2, p. 99-108.
Linyuchev, V. P., Ban'kovskii, A. I. Alkaloids of Galega officinalis. Trudy vsesoyuz. nauch.-issledovatel. inst. lekarstv. i aromat. rast., 1959, vol. (No. 11), p. 65-9.
Roch, N., Buronfosse, F., Grancher, D. Cattle poisoning by French honeysuckle (Galega officinalis L.). Revue de medecine veterinaire, 2007, vol. 158, no. 1, p. 3-6.
Rasekh, Hamid R., Nazari, Pardis., Kamli-Nejad, Mohammad., Hosseinzadeh, Leila. Acute and subchronic oral toxicity of Galega officinalis in rats. Journal of ethnopharmacology, 2008, vol. 116, no. 1, p. 21-26. DOI
Rosca, M., Tamas, M. Studies on Galegae Herba products. Farmacia (bucharest, romania), 1988, vol. 36, no. 4, p. 217-21.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature