Botanical species · safety record

Garcinia hanburyi

The EFSA Compendium of Botanicals holds 5 constituent measurements and 2 adverse-effect records for Garcinia hanburyi. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Garcinia hanburyi Hook.f.

5Constituent measurements
2Safety records
6Cited sources
0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

  • Gambogic acid3
  • Morellin1
  • Xanthones1

Plant parts

  • Live plants5
  • Unspecified1

Preparations

  • Solvent extraction5
  • Latex (as part-nature)1

Effect types

  • Nephrotoxicity1
  • Teratogenic1

Target tissues

  • Muscle, skeletal1
  • Urogenital: kidneys1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
Gambogic acidLive plantsSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
Gambogic acidLive plantsSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
Gambogic acidLive plantsSolvent extractionHPLC with standard detection methodsResolve DOI
MorellinLive plantsSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
XanthonesLive plantsSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
NephrotoxicityUrogenital: kidneysUnspecifiedLatex (as part-nature)Rat (as animal)Chronic/long term toxicityResolve DOI
TeratogenicMuscle, skeletalRat (as animal)Reproduction toxicityResolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Zhao, Li., Zhen, Chen., Wu, Zhaoqiu., Hu, Rong., Zhou, Changlin., Guo, Qinglong. General pharmacological properties, developmental toxicity, and analgesic activity of gambogic acid, a novel natural anticancer agent . Drug and chemical toxicology, 2010, vol. 33, no. 1, p. 88-96. DOI
  2. Qi, Qi., You, Qidong., Gu, Hongyan., Zhao, Li., Liu, Wei., Lu, Na., Guo, Qinglong. Studies on the toxicity of gambogic acid in rats. Journal of ethnopharmacology, 2008, vol. 117, no. 3, p. 433-438. DOI
  3. LIN, LJ., LIN, LZ., PEZZUTO, JM., CORDELL, GA., RUANGRUNGSI, N. ISOGAMBOGIC ACID AND ISOMORELLINOL FROM GARCINIA-HANBURYI. Magnetic resonance in chemistry, 1993, vol. 31, no. 4, p. 340-347. DOI
  4. Reutrakul, Vichai., Anantachoke, Natthinee., Pohmakotr, Manat., Jaipetch, Thaworn., Sophasan, Samaisukh., Yoosook, Chalobon., Kasisit, Jittra., Napaswat, Chanita., Santisuk, Thawatchai., Tuchinda, Patoomratana. Cytotoxic and anti-HIV-1 caged xanthones from the resin and fruits of Garcinia hanburyi . Planta medica, 2007, vol. 73, no. 1, p. 33-40. DOI
  5. Xu, Min., Fu, Wenwei., Zhang, Baojun., Tan, Hongsheng., Xiu, Yanfeng., Xu, Hongxi. Combinative application of pH-zone-refining and conventional high-speed counter-current chromatography for preparative separation of caged polyprenylated xanthones from gamboge . Journal of separation science, 2016, vol. 39, no. 3, p. 559-565. DOI
  6. Tao, Si-Jia., Guan, Shu-Hong., Wang, Wei., Lu, Zhi-Qiang., Chen, Guang-Tong., Sha, Na., Yue, Qing-Xi., Liu, Xuan., Guo, De-An. Cytotoxic Polyprenylated Xanthones from the Resin of Garcinia hanburyi. Journal of natural products, 2009, vol. 72, no. 1, p. 117-124. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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