Botanical species · safety record

Gardenia jasminoides

The EFSA Compendium of Botanicals holds 2 constituent measurements, 1 adverse-effect record and 1 genotoxicity assay for Gardenia jasminoides. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Gardenia jasminoides J.Ellis

2Constituent measurements
2Safety records
3Cited sources
742Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 742 licensed products naming Gardenia jasminoides as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

  • Dry
  • Extract Type TBA
  • Fresh
  • solid

Source material stated

  • Dried ripe fruit
  • Fruit
  • Fruit (Stir-baked with ginger)
  • Fruit (dry-fried)
  • Fruit (fried with wine)
  • Fruit (fried)
  • Fruit (processed with ginger)
  • Fruit (processed)

What the records describe

Constituents measured

  • Emodin1
  • Physcion1

Plant parts

  • Flower2

Effect types

  • Hepatotoxicity1

Target tissues

  • Liver1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
EmodinFlowerNuclear Magnetic Resonance (NMR)No resolvable identifier
PhyscionFlowerNuclear Magnetic Resonance (NMR)No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
HepatotoxicityLiverRat (as animal)Acute toxicityResolve DOI

Genotoxicity testing

Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.

OutcomeEndpointTestTested organismMetabolic activationSource
Positivechromosome aberrationsister chromatid exchange assay in mammalian cellsOtherNot applicableResolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Ozaki, A., Kitano, M., Furusawa, N., Yamaguchi, H., Kuroda, K., Endo, G. Genotoxicity of gardenia yellow and its components. FOOD AND CHEMICAL TOXICOLOGY, 2002, vol. 40, no. 11, p. 1603-1610. DOI
  2. Ding, Yue., Zhang, Tong., Tao, Jian-sheng., Zhang, Li-ying., Shi, Jian-rong., Ji, Guang. Potential hepatotoxicity of geniposide, the major iridoid glycoside in dried ripe fruits of Gardenia jasminoides (Zhi-zi) . Natural product research, 2013, vol. 27, no. 10, p. 929-933. DOI
  3. Song, Jia-Ling., Yang, Yong-Jian., Qi, Huan-Yang., Li, Qiang. Chemical constituents from flowers of Gardenia jasminoides .. Zhong yao cai = zhongyaocai = journal of chinese medicinal materials, 2013, vol. 36, no. 5, p. 752-5.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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