Botanical species · safety record

Gelsemium sempervirens

The EFSA Compendium of Botanicals holds 6 constituent measurements and 1 adverse-effect record for Gelsemium sempervirens. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Gelsemium sempervirens (L.) J.St.-Hil.

6Constituent measurements

1Safety records

3Cited sources

233Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 233 licensed products naming Gelsemium sempervirens as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

Dried root(s)
Dried subterranean parts
Dried underground organs
Fresh underground part(s)
Fresh underground parts
Gelsemium sempervirens (L.) Jaume St.-Hil., fresh underground parts
Parties souterraines fraîches
Racine

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Alkaloids	Unspecified	—	—	Unspecified	Resolve DOI
Coumarins	Aerial part of plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Gelsemine	Aerial part of plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Scopoletin	Aerial part of plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Sempervirin	Aerial part of plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Indole alkaloids	Live plants	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Neurotoxicity	Neurologic: central nervous system	Leaves	—	Goat (as animal)	Case report	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Zhang, Zhizhen., Wang, Ping., Yuan, Wei., Li, Shiyou. Steroids, Alkaloids, and Coumarins from Gelsemium sempervirens. Planta medica, 2008, vol. 74, no. 15, p. 1818-1822. DOI
LIN, LZ., YEH, S., CORDELL, GA., NI, CZ., CLARDY, J. 3 OXINDOLE ALKALOIDS FROM GELSEMIUM SPECIES. Phytochemistry, 1991, vol. 30, no. 2, p. 679-683.
Dutt, V., Thakur, S., Dhar, V J., Sharma, A. The genus Gelsemium: An update.. Pharmacognosy reviews, 2010, vol. 4, no. 8, p. 185-94. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature