Botanical species · safety record

Gentiana cruciata

The EFSA Compendium of Botanicals holds 4 constituent measurements and 1 genotoxicity assay for Gentiana cruciata. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Gentiana cruciata L.

4Constituent measurements

1Safety records

2Cited sources

2Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 2 licensed products naming Gentiana cruciata as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

Root

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Alkaloids	Aerial part of plants	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Coumarins	Aerial part of plants	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Gallic acid	Aerial part of plants	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Tannins	Aerial part of plants	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier

Genotoxicity testing

Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.

Outcome	Endpoint	Test	Tested organism	Metabolic activation	Source
Positive	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	Rat (as animal)	Not applicable	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Mihailovic, Vladimir., Misic, Danijela., Matic, Sanja., Mihailovic, Mirjana., Stanic, Snezana., Vrvic, Miroslav M., Katanic, Jelena., Mladenovic, Milan., Stankovic, Nevena., Boroja, Tatjana., Stankovic, Milan S. Comparative phytochemical analysis of Gentiana cruciata L. roots and aerial parts, and their biological activities. INDUSTRIAL CROPS AND PRODUCTS, 2015, vol. 73, p. 49-62. DOI
Borovik, T.S., Pribytkova, L.N. Devoted to comparative chemical and anatomical analysis of species <i>Gentiana</i>, which are growing on Western Siberia . Voprosy biologicheskoi, meditsinskoi i farmatsevticheskoi khimii, 2014, no. 12, p. 33-34.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature