Botanical species · safety record

Gentiana macrophylla

The EFSA Compendium of Botanicals holds 5 constituent measurements for Gentiana macrophylla. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Gentiana macrophylla Pall.

5Constituent measurements

0Safety records

5Cited sources

167Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 167 licensed products naming Gentiana macrophylla as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Dry
Extract Type TBA
decoction

Source material stated

New material
Radix
Rhizome
Root
Whole plant

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Alkaloids	Roots and other underground parts	Solvent extraction	—	—	No resolvable identifier
Alkaloids	Roots and other underground parts	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Alkaloids	Unspecified	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Artemisinin	Unspecified	Solvent extraction	—	Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)	No resolvable identifier
Coumarins	Roots and other underground parts	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Liu, Keng-T'ao., Chi, Hsiu-Chuan., Sung, Chen-Yu. The toxicity and pharmacology of gentianine, an alkaloid isolated from Gentiana macrophylla. Shengli xuebao, 1959, p. 203-210.
Sun, Fengli., Yang, Lixin., Cui, Shulian. Quality standard study on Fufang Haoqin Fengshi Capsule. Zhongguo shiyan fangjixue zazhi, 2009, p. 15-17.
Wang, Xiaoyan. Determination of alkaloids in largeleaf gentian (Gentiana macrophylla) and its adulterats. Zhongcaoyao, 1993, p. 189-190.
Huang, Huan., Zhang, Xiaoyu., Zhang, Hong., Yan, Na. RP-HPLC-PDA determination of gentiopicrin and dl-tetrahydropalmatine in Gentiana macrophylla and Corydalis yanhusuo W. T. Wan. Yaowu fenxi zazhi, 2007, p. 1029-1032.
Chen, Qian-Liang., Shi, Zhang-Yan., Tu, Guang-Zhong., Sun, Wen-Ji. Studies on the chemical constituents in root of Gentiana macrophylla from Shaanxi . . Zhongguo zhong yao za zhi = zhongguo zhongyao zazhi = china journal of chinese materia medica, 2005, vol. 30, no. 19, p. 1519-22.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature