Botanical species · safety record

Globularia alypum

The EFSA Compendium of Botanicals holds 5 constituent measurements and 3 adverse-effect records for Globularia alypum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Globularia alypum L.

5Constituent measurements

3Safety records

6Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Eleutheroside b	Leaves	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Lignans	Leaves	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Alkaloids	Aerial part of plants	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Salicylic acid	Live plants	Solvent extraction	—	—	No resolvable identifier
Tannins	Leaves	Solvent extraction	—	Phytochemical screening	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Reproductive	Uterus	Leaves	Solvent extraction	Rat (as animal)	Reproduction toxicity	Resolve DOI
Reproductive	Uterus	Leaves	Solvent extraction	Rat (as animal)	Reproduction toxicity	Resolve DOI
Systemic	Lung	Leaves	Solvent extraction	Rat (as animal)	Short-term toxicity	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Fehri, Badreddine., Aiache, Jean-Marc., Ahmed, Kk Mueen. Active spermatogenesis induced by a reiterated administration of Globularia alypum L. aqueous leaf extract. . Pharmacognosy research, 2012, vol. 4, no. 3, p. 138-47. DOI
Elbetieha, A., Oran, SA., Alkofahi, A., Darmani, H., Raies, AM. Fetotoxic potentials of Globularia arabica and Globularia alypum (Globulariaceae) in rats . Journal of ethnopharmacology, 2000, vol. 72, no. 1-2, p. 215-219. DOI
Ben Hassine, Bechir., Bui, A., Mighri, Z. Study of Tunisian medicinal plants. Identification of phenolic acids of Globularia alypum L. by two-dimensional thin-layer chromatography and HPLC. Journal de la societe chimique de tunisie, 1982, vol. 7, p. 3-10.
Viladomat, F., Codina, C., Llabres, J. M., Bastida, J. Alkaloid screening of plants of Catalonia (Spain). III. International journal of crude drug research, 1986, vol. 24, no. 3, p. 123-30.
Kirmizibekmez, Hasan., Bassarello, Carla., Piacente, Sonia., Calis, Ihsan. Phenylethyl glycosides from Globularia alypum growing in Turkey. Helvetica chimica acta, 2008, vol. 91, no. 8, p. 1525-1532. DOI
Harzallah, Hanene Jrah., Neffati, Aicha., Skandrani, Ines., Maaloul, Eya., Chekir-Ghedira, Leila., Mahjoub, Touhami. Antioxidant and antigenotoxic activities of Globularia alypum leaves extracts . Journal of medicinal plants research, 2010, vol. 4, no. 19, p. 2048-2053.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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