Botanical species · safety record
Gloriosa superba
The EFSA Compendium of Botanicals holds 6 constituent measurements and 8 adverse-effect records for Gloriosa superba. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Gloriosa superba L.
Regulatory presence
No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.
What the records describe
Constituents measured
- Alkaloids2
- Colchicin1
- Saponins1
- Steroids1
- Tannins1
Plant parts
- Roots and other underground parts used as staple food6
- Aerial part of plants4
- Roots and other underground parts3
- Unspecified1
Preparations
- Solvent extraction8
- Thermal treatment (heating for preservation)1
Effect types
- Digestive4
- Endocrine1
- Neurotoxicity1
- Reproductive1
- Systemic1
Target tissues
- Liver3
- Brain1
- Skin1
- Stomach1
- Testes1
- Uterus1
- subcutis1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Alkaloids | Aerial part of plants | Solvent extraction | — | Phytochemical screening | No resolvable identifier |
| Alkaloids | Roots and other underground parts | Solvent extraction | — | Phytochemical screening | No resolvable identifier |
| Colchicin | Roots and other underground parts used as staple food | — | 0.6 Milligram/gram | — | No resolvable identifier |
| Saponins | Aerial part of plants | Solvent extraction | — | Phytochemical screening | No resolvable identifier |
| Steroids | Aerial part of plants | Solvent extraction | — | Phytochemical screening | No resolvable identifier |
| Tannins | Roots and other underground parts | Solvent extraction | — | Phytochemical screening | No resolvable identifier |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Digestive | Liver | Roots and other underground parts used as staple food | — | Human (as organism) | Case report | Resolve DOI |
| Digestive | Liver | Unspecified | — | Human (as organism) | Case report | Resolve DOI |
| Neurotoxicity | Brain | Roots and other underground parts used as staple food | — | Human (as organism) | Case report | Resolve DOI |
| Systemic | Liver | Roots and other underground parts used as staple food | — | Human (as organism) | Case report | Resolve DOI |
| Digestive | Skin/subcutis | Roots and other underground parts used as staple food | Thermal treatment (heating for preservation) | Human (as organism) | Case report | No resolvable identifier |
| Digestive | Stomach | Roots and other underground parts used as staple food | Solvent extraction | Rat (as animal) | Acute toxicity | No resolvable identifier |
| Endocrine | Testes | Aerial part of plants | Solvent extraction | Rat (as animal) | Short-term toxicity | No resolvable identifier |
| Reproductive | Uterus | Roots and other underground parts | Solvent extraction | Rat (as animal) | Reproduction toxicity | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Malpani, Arati A., Aswar, Urmila M., Kushwaha, Shiv K., Zambare, G. N., Bodhankar, S. L. Effect of the Aqueous Extract of Gloriosa superba Linn (Langli) Roots on Reproductive System and Cardiovascular Parameters in Female Rats . Tropical journal of pharmaceutical research, 2011, vol. 10, no. 2, p. 169-176.
- Gooneratne, Inuka Kishara., Weeratunga, Praveen., Caldera, Manjula., Gamage, Ranjanie. Toxic encephalopathy due to colchicine--Gloriosa superba poisoning.. Practical neurology, 2014, vol. 14, no. 5, p. 357-9. DOI
- Jayatilaka, A. D. P., Balasubramaniam, K., Dunuwille, R., Bibile, S. W. Histological studies of the gastrointestinal tract of the rat after poisoning with tuber of Gloriosa superba. Ceylon journal of medical science, 1967, vol. 16(1-2), p. 11-17.
- Lucas, G. N. Plant poisoning: A hospital-based study in Sri Lanka. Indian journal of pediatrics, 1997, vol. 64, no. 4, p. 495-502. DOI
- Babu, Y. P. Raghavendra., Manjunath, S., Bakkannavar, Shankar M., Acharya, Jenash., Kumar, G. N. Pramod. Colchicine poisoning: a case report and review of literature. Medicine science and the law, 2012, vol. 52, no. 4, p. 205-206. DOI
- Pare, S. R., Zade, V. S., Thakare, V. G. Evaluation of the potential aphrodisiac activity of aqueous, chloroform and alcohol extract of Gloriosa superba in male albino rat. International journal of theoretical and applied sciences, 2014, vol. 6, no. 2), 39-4, p. 8 pp.
- Premaratna, Ranjan., Weerasinghe, Mindu S., Premawardana, Nuwan. P., de Silva, H. Janaka. Gloriosa superba poisoning mimicking an acute infection- a case report. Bmc pharmacology & toxicology, 2015, vol. 16. DOI
- Kageyama, Tomoko., Takahashi, Makoto., Maeda, Tomoyuki., Shimamoto, Sayaka., Yokoyama, Reiko., Owada, Kazuhiro., Sakane, Yumiko., Yamamoto, Masatoshi. Qualitative and quantitative analysis of colchicine using LC/MS(/MS) and HPLC in the case of poisoning by tuber of Gloriosa superba linnaeus. Shizuoka-ken kankyo eisei kagaku kenkyusho hokoku, 2007, vol. 50, p. 41-44.
- GOONERATNE, BW. MASSIVE GENERALIZED ALOPECIA AFTER POISONING BY GLORIOSA SUPERBA. Bmj-british medical journal, 1966, vol. 1, no. 5494, p. 1023-+.
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
Continue
Europe PMC
Every record indexed for this species, resolvable and re-runnable.
All speciesSubstance index
Search and browse every species this world holds under source and hash.
Before anything elseSafety Centre
Interactions, contraindications and the escalation boundary this world does not cross.
In its own termsTraditions
How the living traditions approach preparation, use and context.