Botanical species · safety record

Gloriosa superba

The EFSA Compendium of Botanicals holds 6 constituent measurements and 8 adverse-effect records for Gloriosa superba. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Gloriosa superba L.

6Constituent measurements
8Safety records
9Cited sources
0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

  • Alkaloids2
  • Colchicin1
  • Saponins1
  • Steroids1
  • Tannins1

Plant parts

  • Roots and other underground parts used as staple food6
  • Aerial part of plants4
  • Roots and other underground parts3
  • Unspecified1

Preparations

  • Solvent extraction8
  • Thermal treatment (heating for preservation)1

Effect types

  • Digestive4
  • Endocrine1
  • Neurotoxicity1
  • Reproductive1
  • Systemic1

Target tissues

  • Liver3
  • Brain1
  • Skin1
  • Stomach1
  • Testes1
  • Uterus1
  • subcutis1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
AlkaloidsAerial part of plantsSolvent extractionPhytochemical screeningNo resolvable identifier
AlkaloidsRoots and other underground partsSolvent extractionPhytochemical screeningNo resolvable identifier
ColchicinRoots and other underground parts used as staple food0.6 Milligram/gramNo resolvable identifier
SaponinsAerial part of plantsSolvent extractionPhytochemical screeningNo resolvable identifier
SteroidsAerial part of plantsSolvent extractionPhytochemical screeningNo resolvable identifier
TanninsRoots and other underground partsSolvent extractionPhytochemical screeningNo resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
DigestiveLiverRoots and other underground parts used as staple foodHuman (as organism)Case reportResolve DOI
DigestiveLiverUnspecifiedHuman (as organism)Case reportResolve DOI
NeurotoxicityBrainRoots and other underground parts used as staple foodHuman (as organism)Case reportResolve DOI
SystemicLiverRoots and other underground parts used as staple foodHuman (as organism)Case reportResolve DOI
DigestiveSkin/subcutisRoots and other underground parts used as staple foodThermal treatment (heating for preservation)Human (as organism)Case reportNo resolvable identifier
DigestiveStomachRoots and other underground parts used as staple foodSolvent extractionRat (as animal)Acute toxicityNo resolvable identifier
EndocrineTestesAerial part of plantsSolvent extractionRat (as animal)Short-term toxicityNo resolvable identifier
ReproductiveUterusRoots and other underground partsSolvent extractionRat (as animal)Reproduction toxicityNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Malpani, Arati A., Aswar, Urmila M., Kushwaha, Shiv K., Zambare, G. N., Bodhankar, S. L. Effect of the Aqueous Extract of Gloriosa superba Linn (Langli) Roots on Reproductive System and Cardiovascular Parameters in Female Rats . Tropical journal of pharmaceutical research, 2011, vol. 10, no. 2, p. 169-176.
  2. Gooneratne, Inuka Kishara., Weeratunga, Praveen., Caldera, Manjula., Gamage, Ranjanie. Toxic encephalopathy due to colchicine--Gloriosa superba poisoning.. Practical neurology, 2014, vol. 14, no. 5, p. 357-9. DOI
  3. Jayatilaka, A. D. P., Balasubramaniam, K., Dunuwille, R., Bibile, S. W. Histological studies of the gastrointestinal tract of the rat after poisoning with tuber of Gloriosa superba. Ceylon journal of medical science, 1967, vol. 16(1-2), p. 11-17.
  4. Lucas, G. N. Plant poisoning: A hospital-based study in Sri Lanka. Indian journal of pediatrics, 1997, vol. 64, no. 4, p. 495-502. DOI
  5. Babu, Y. P. Raghavendra., Manjunath, S., Bakkannavar, Shankar M., Acharya, Jenash., Kumar, G. N. Pramod. Colchicine poisoning: a case report and review of literature. Medicine science and the law, 2012, vol. 52, no. 4, p. 205-206. DOI
  6. Pare, S. R., Zade, V. S., Thakare, V. G. Evaluation of the potential aphrodisiac activity of aqueous, chloroform and alcohol extract of Gloriosa superba in male albino rat. International journal of theoretical and applied sciences, 2014, vol. 6, no. 2), 39-4, p. 8 pp.
  7. Premaratna, Ranjan., Weerasinghe, Mindu S., Premawardana, Nuwan. P., de Silva, H. Janaka. Gloriosa superba poisoning mimicking an acute infection- a case report. Bmc pharmacology & toxicology, 2015, vol. 16. DOI
  8. Kageyama, Tomoko., Takahashi, Makoto., Maeda, Tomoyuki., Shimamoto, Sayaka., Yokoyama, Reiko., Owada, Kazuhiro., Sakane, Yumiko., Yamamoto, Masatoshi. Qualitative and quantitative analysis of colchicine using LC/MS(/MS) and HPLC in the case of poisoning by tuber of Gloriosa superba linnaeus. Shizuoka-ken kankyo eisei kagaku kenkyusho hokoku, 2007, vol. 50, p. 41-44.
  9. GOONERATNE, BW. MASSIVE GENERALIZED ALOPECIA AFTER POISONING BY GLORIOSA SUPERBA. Bmj-british medical journal, 1966, vol. 1, no. 5494, p. 1023-+.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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