Botanical species · safety record

Gossypium arboreum

The EFSA Compendium of Botanicals holds 3 constituent measurements and 8 adverse-effect records for Gossypium arboreum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Gossypium arboreum L.

3Constituent measurements

8Safety records

3Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Tannins	Leaves	Solvent extraction	—	Phytochemical screening	Resolve DOI
Free gossypol	Seed	Powder	≥ 54.8 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Free gossypol	Seed	Powder	≤ 78.8 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Digestive	Digestive	Leaves	Solvent extraction	—	In vitro	Resolve DOI
Digestive	Digestive	Leaves	Solvent extraction	—	In vitro	Resolve DOI
Digestive	Digestive	Leaves	Solvent extraction	—	In vitro	Resolve DOI
Digestive	Digestive	Leaves	Solvent extraction	—	In vitro	Resolve DOI
Hepatotoxicity	Liver	Seed	—	Gallus gallus (chicken) (as animal)	Short-term toxicity	Resolve DOI
Immunotoxicity	Cardiovascular / haematological: lymph nodes	Seed	—	House mouse (as animal)	Not reported	Resolve DOI
Reproductive	Testes	Seed	—	Hamster (as animal)	Reproduction toxicity	Resolve DOI
Systemic	Respiratory	Seed	—	Mammals (as animal)	Acute toxicity	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Gadelha, Ivana Cristina N., Fonseca, Nayanna Brunna S., Oloris, Silvia Catarina S., Melo, Marilia M., Soto-Blanco, Benito. Gossypol Toxicity from Cottonseed Products. Scientific world journal, 2014. DOI
Kazeem, Mutiu Idowu., Abimbola, Stella Gbemisola., Ashafa, Anofi Omotayo Tom. Inhibitory potential of Gossypium arboreum leaf extracts on diabetes key enzymes, alpha-amylase and alpha-glucosidase . Bangladesh journal of pharmacology, 2013, vol. 8, no. 2, p. 149-155. DOI
Stipanovic, Robert D., Puckhaber, Lorraine S., Bell, Alois A., Percival, Albert E., Jacobs, John. Occurrence of (+)- and (-)-Gossypol in Wild Species of Cotton and in Gossypium hirsutum Var. marie-galante (Watt) Hutchinson. Journal of agricultural and food chemistry, 2005, vol. 53, no. 16, p. 6266-6271.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature