Botanical species · safety record

Gossypium herbaceum

The EFSA Compendium of Botanicals holds 2 constituent measurements and 2 adverse-effect records for Gossypium herbaceum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Gossypium herbaceum L.

2Constituent measurements
2Safety records
3Cited sources
14Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 14 licensed products naming Gossypium herbaceum as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

  • Root bark
  • Seed extract
  • Seed(s)

What the records describe

Constituents measured

  • Free gossypol2

Plant parts

  • Seed3

Preparations

  • Solvent extraction2

Effect types

  • Developmental1
  • Systemic1

Target tissues

  • Cardiovascular1
  • Uterus1
  • haematological1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
Free gossypolSeedSolvent extraction≤ 71 PercentHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier
Free gossypolSeedSolvent extraction≥ 59.3 PercentHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
DevelopmentalUterusSeedRat (as animal)Reproduction toxicityNo resolvable identifier
SystemicCardiovascular / haematologicalRat (as animal)Short-term toxicityNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Mello, Joao R. B., Mello, Fernanda B., Etges, Rodrigo N., Hollenbach, Clarissa., Rodrigues, Juliano M., Hirtz, Lucas. Pre-clinic toxicity of a phytotherapic containing Gossypium herbaceum (cotton plant) in Wistar rats . Latin american journal of pharmacy, 2008, vol. 27, no. 1, p. 46-55.
  2. Nath, D., Sethi, N., Srivastava, S., Jain, A. K., Srivastava, R. Teratogenic evaluation of an indigenous antifertility medicinal plant Gossypium herbaceum in rat . Fitoterapia, 1997, vol. 68, no. 2, p. 137-139.
  3. Stipanovic, Robert D., Puckhaber, Lorraine S., Bell, Alois A., Percival, Albert E., Jacobs, John. Occurrence of (+)- and (-)-Gossypol in Wild Species of Cotton and in Gossypium hirsutum Var. marie-galante (Watt) Hutchinson. Journal of agricultural and food chemistry, 2005, vol. 53, no. 16, p. 6266-6271.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

Continue