Botanical species · safety record

Guaiacum officinale

The EFSA Compendium of Botanicals holds 12 constituent measurements for Guaiacum officinale. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Guaiacum officinale L.

12Constituent measurements

0Safety records

8Cited sources

12Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 12 licensed products naming Guaiacum officinale as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Source material stated

Resin
Resin powder
Stem resin
Wood

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Guaiacin	Leaves	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Pentacyclic triterpene saponins	Bark	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Saponins	Fruit unspecified	Solvent extraction	—	HPLC with standard detection methods	Resolve DOI
Saponins	Flower	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
(-)-guaiaretic acid	Wood	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Alpha-guaiaconic acid	Wood	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Guaiacin	Wood	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Isoguaiacin	Wood	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Lignans	Wood	Solvent extraction	—	HPLC with standard detection methods	No resolvable identifier
Meso-dihydroguaiaretic acid	Wood	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Pentacyclic triterpene saponins	Fruit unspecified	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Triterpene saponins	Bark	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

AHMAD, VU., UDDIN, S., BANO, S., FATIMA, I. 2 SAPONINS FROM FRUITS OF GUAIACUM-OFFICINALE. Phytochemistry, 1989, vol. 28, no. 8, p. 2169-2171. DOI
Chavez, Kathryn J., Feng, Xiaohong., Flanders, James A., Rodriguez, Eloy., Schroeder, Frank C. Spirocyclic Lignans from Guaiacum (Zygophyllaceae) Induce Apoptosis in Human Breast Cancer Cell Lines. Journal of natural products, 2011, vol. 74, no. 5, p. 1293-1297.
Saba, Nikhat., Ahmad, Viqar Uddin., Ali, Zulfiqar., Khan, Khalid Mohammed. Separation and identification of anew saponin from the flowers of Guaiacum officinale L. . Natural product research, 2010, vol. 24, no. 20, p. 1877-1882. DOI
Saba, Nikhat., Khatoon, Rasheeda., Ali, Zulfiqar., Ahmad, Viqar Uddin. A New Bidesmoside Saponin from the Bark of Guaiacum officinale. Journal of the chemical society of pakistan, 2012, vol. 34, no. 2, p. 448-450.
Alves, TMD., Nagem, TJ., Ribeiro, A., Mendes, NM., Gomez, JD., Zani, CL., Hamburger, M., Hostettmann, K. Molluscicidal saponins from Guaiacum officinale (Zygophyllaceae). International journal of pharmacognosy, 1996, vol. 34, no. 2, p. 81-86.
Ahmad, V U., Perveen, S., Bano, S. Guaiacin A and B from the Leaves of Guaiacum officinale.. Planta medica, 1989, vol. 55, no. 3, p. 307-8. DOI
AHMAD, VU., BANO, N., BANO, S. SAPOGENINS FROM GUAIACUM-OFFICINALE. Phytochemistry, 1984, vol. 23, no. 11, p. 2613-2616. DOI
King, F.E., Wilson, J.G. The chemistry of extractives from hardwoods. Part XXXVI. The lignans of guaiacum officinale L. Journal of the chemical society (resumed), 1964, p. 4008-4011.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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