Botanical species · safety record
Gypsophila paniculata
The EFSA Compendium of Botanicals holds 8 constituent measurements and 2 adverse-effect records for Gypsophila paniculata. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Gypsophila paniculata L.
Regulatory presence
No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.
What the records describe
Constituents measured
- Gypsogenin3
- Saponins2
- Triterpene saponins2
- Quillaic acid1
Plant parts
- Roots and other underground parts7
- Live plants2
Preparations
- Solvent extraction6
- Powder2
Effect types
- Digestive2
Target tissues
- Digestive2
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Gypsogenin | Roots and other underground parts | Solvent extraction | ≤ 0.34 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Gypsogenin | Roots and other underground parts | Solvent extraction | ≥ 0.11 Milligram/gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Gypsogenin | Roots and other underground parts | Powder | 0.52 Percent | HPLC with standard detection methods | Resolve DOI |
| Quillaic acid | Roots and other underground parts | Powder | 0.3 Percent | HPLC with standard detection methods | Resolve DOI |
| Triterpene saponins | Roots and other underground parts | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Saponins | Live plants | Solvent extraction | 19 Percent | Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) | No resolvable identifier |
| Saponins | Live plants | — | — | — | No resolvable identifier |
| Triterpene saponins | Roots and other underground parts | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | No resolvable identifier |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Digestive | Digestive | Roots and other underground parts | Solvent extraction | — | In vitro | Resolve DOI |
| Digestive | Digestive | — | — | — | In vitro | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Yao, Shun., Ma, Li., Luo, Jian-Guang., Wang, Jun-Song., Kong, Ling-Yi. New Triterpenoid Saponins from the Roots of Gypsophila paniculata L.. Helvetica chimica acta, 2010, vol. 93, no. 2, p. 361-374.
- Yao Shun., Luo Jian-Guang., Ma Li., Kong Ling-Yi. Two New Triterpenoid Saponins from the Roots of Gypsophila paniculata with Potent alpha-Glucosidase Inhibition Activity . Chinese journal of natural medicines, 2011, vol. 9, no. 6, p. 401-405. DOI
- Kolodziejski, I. Jozef., Stecka, Leokadia. Occurrence of saponins in various parts of Gypsophila paniculata and Gypsophila altissima. Farmacja polska, 1965, p. 751-754.
- Vacek, Lubor., Sedlak, Bretislav. Comparison of physical, chemical, and biological properties of saponins. Gunma journal of medical sciences, 1962, p. 1-6.
- Gevrenova, R., Joubert, O., Mandova, Tsv., Zaiou, M., Chapleur, Y., Henry, M. Cytotoxic effects of four Caryophyllaceae species extracts on macrophage cell lines . Pharmaceutical biology, 2014, vol. 52, no. 7, p. 919-925. DOI
- Gevrenova, Reneta., Stancheva, Tanya., Voynikov, Yulian., Laurain-Mattar, Dominique., Henry, Max. Root in vitro cultures of six Gypsophila species and their saponin contents . Enzyme and microbial technology, 2010, vol. 47, no. 3, p. 97-104. DOI
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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