Botanical species · safety record
Haplophyllum perforatum
The EFSA Compendium of Botanicals holds 13 constituent measurements for Haplophyllum perforatum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Haplophyllum perforatum (M. Bieb.) Vved.
Also recorded as
Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.
Regulatory presence
No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.
What the records describe
Constituents measured
- Alkaloids2
- Coumarins2
- Haplamine2
- Haplopine2
- Skimmianine2
- 1,8-cineole1
- Camphor1
- Myrcene1
Plant parts
- Leaves7
- Unspecified3
- Flower2
- Aerial part of plants1
Preparations
- Solvent extraction6
- Essential oil3
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| 1,8-cineole | Flower | Essential oil | 22.8 Percent | Gaschromatography (GC) | Resolve DOI |
| Alkaloids | Aerial part of plants | — | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Camphor | Flower | Essential oil | 19.9 Percent | Gaschromatography (GC) | Resolve DOI |
| Haplamine | Leaves | Solvent extraction | ≤ 5.24 Percent | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Haplamine | Leaves | Solvent extraction | ≥ 1.23 Percent | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Haplopine | Leaves | Solvent extraction | ≥ 0.43 Percent | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Haplopine | Leaves | Solvent extraction | ≤ 0.8 Percent | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Myrcene | Leaves | Essential oil | 1 Percent | Gaschromatography (GC) | Resolve DOI |
| Skimmianine | Leaves | Solvent extraction | ≤ 2.75 Percent | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Skimmianine | Leaves | Solvent extraction | ≥ 0.1 Percent | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Alkaloids | Unspecified | — | — | Unspecified | No resolvable identifier |
| Coumarins | Unspecified | — | — | Unspecified | No resolvable identifier |
| Coumarins | Unspecified | — | — | Unspecified | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Fiot, Julien., Jansen, Olivia., Akhmedjanova, Valentina., Angenot, Luc., Balansard, Guy., Ollivier, Evelyne. HPLC quantification of alkaloids from Haplophyllum extracts and comparison with their cytotoxic properties . Phytochemical analysis, 2006, vol. 17, no. 5, p. 365-369. DOI
- Aminov, S. D., Vakhabov, A. A. Pharmacology of some coumarins isolated from the plant Haplophyllum. Doklady akademii nauk uzssr, 1985, p. 44-45.
- Mohammadhosseini, Majid., Nekoei, Mehdi., Mashayekhi, Hossein Ali., Aboli, Jafar. Chemical Composition of the Essential Oil from Flowers, Leaves and Stems of Haplophyllum perforatum by Using Head Space Solid Phase Microextraction . Journal of essential oil bearing plants, 2012, vol. 15, no. 4, p. 506-515. DOI
- Jansen, O., Akhmedjanova, V., Angenot, L., Balansard, G., Chariot, A., Ollivier, E., Tits, M., Frederich, M. Screening of 14 alkaloids isolated from Haplophyllum A. Juss. for their cytotoxic properties . Journal of ethnopharmacology, 2006, vol. 105, no. 1-2, p. 241-245. DOI
- Polievtsev, N. P., Kamilov, I. K. Pharmacology of the alkaloid, haploperin (eudoxin). Farmakol. alk. (tashkent: nauka), 1965, p. 14-22.
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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