Botanical species · safety record

Harpagophytum procumbens

The EFSA Compendium of Botanicals holds 1 constituent measurement and 4 adverse-effect records for Harpagophytum procumbens. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Harpagophytum procumbens (Burch.) DC. ex Meisn.

1Constituent measurements

4Safety records

4Cited sources

707Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 707 licensed products naming Harpagophytum procumbens as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Dry
Extract Type TBA
fluid
solid

Source material stated

Aged bark
Chopped, dried, thick, seconday roots
Devil's claw from secondary root tubers
Dried secondary root tuber
Dried secondary root tuber extract
Dried secondary roots
Harpagophytum procumbens - Secondary root tuber
Harpagophytum procumbens, roots

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Triterpene saponins	Roots and other underground parts	—	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Digestive	Stomach	Roots and other underground parts	Solvent extraction	Human (as organism)	Case report	Resolve DOI
Digestive	Stomach	Roots and other underground parts	—	Human (as organism)	Case report	No resolvable identifier
Digestive	Digestive	Unspecified	—	—	Acute toxicity	No resolvable identifier
Pulmonary and cardiac	Heart	Roots and other underground parts	—	Human (as organism)	Case report	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Vlachojannis, J., Roufogalis, B. D., Chrubasik, S. Systematic review on the safety of Harpgoophytum preparations for osteoarthritic and low back pain. PHYTOTHERAPY RESEARCH, 2008, vol. 22, no. 2, p. 149-152. DOI
[Anonymous]. Devil's claw root: ulcers and gastrointestinal bleeding?. Prescrire international, 2013, vol. 22, no. 144, p. 296-296.
Vlachojannis J., Roufogalis B D., Chrubasik S. Systematic review on the safety of Harpagophytum preparations for osteoarthritic and low back pain. Phytotherapy research : ptr, 2008, p. 149-152.
Qi, J., Zhou, J.-H., Chen, L., Chen, J.-J., Yu, B.-Y., Qiu, S.-X. Study on chemical constituents in tuber of Harpagophytum procumbens D.C.. Chinese pharmaceutical journal, 2006, vol. 41, no. 21, p. 1613-1615.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature