Botanical species · safety record
Harrisonia abyssinica
The EFSA Compendium of Botanicals holds 9 constituent measurements for Harrisonia abyssinica. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Harrisonia abyssinica Oliv.
Regulatory presence
No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.
What the records describe
Constituents measured
- Atalantolide1
- Chebulagic acid1
- Furan derivatives1
- Harrisonin1
- Obacunone1
- Pedonin1
- Proanthocyanidins (condensed tannins)1
- Tannins1
- Triterpene saponins1
Plant parts
- Bark5
- Leaves2
- Roots and other underground parts1
- Unspecified1
Preparations
- Solvent extraction9
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Atalantolide | Bark | Solvent extraction | 0.8 Milligram/gram | Standard Chromatographic tests (paper- thin layer- and column chromatography) | Resolve DOI |
| Chebulagic acid | Bark | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Harrisonin | Bark | Solvent extraction | 6.2 Milligram/gram | Standard Chromatographic tests (paper- thin layer- and column chromatography) | Resolve DOI |
| Obacunone | Bark | Solvent extraction | 15 Milligram/gram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Pedonin | Bark | Solvent extraction | 10 Milligram/gram | Standard Chromatographic tests (paper- thin layer- and column chromatography) | Resolve DOI |
| Furan derivatives | Roots and other underground parts | Solvent extraction | — | IR and Raman Spectroscopy | No resolvable identifier |
| Proanthocyanidins (condensed tannins) | Leaves | Solvent extraction | 54.3 Milligram/gram | UV/VIS spectroscopy (photometry) | No resolvable identifier |
| Tannins | Leaves | Solvent extraction | 193.3 Milligram/gram | UV/VIS spectroscopy (photometry) | No resolvable identifier |
| Triterpene saponins | Unspecified | Solvent extraction | — | — | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Rubanza, Chrispinus D. K., Shem, Martin N., Ichinohe, Toshiyoshi., Fujihara, Tsutomu. Quantification and characterisation of condensed tannin of selected indigenous browse tree species leaves of north-western Tanzania . Journal of food agriculture & environment, 2008, vol. 6, no. 2, p. 145-149.
- Kareru, P. G., Keriko, J. M., Gachanja, A. N., Kenji, G. M. Direct detection of triterpenoid saponins in medicinal plants. African Journal of Traditional, Complementary and Alternative Medicines, 2008, p. 56-60.
- Rajab, MS., Rugutt, JK., Fronczek, FR., Fischer, NH. Structural revision of harrisonin and 12 beta-acetoxyharrisonin, two limonoids from Harrisonia abyssinica. JOURNAL OF NATURAL PRODUCTS, 1997, vol. 60, no. 8, p. 822-825. DOI
- Kiprop, Ambrose Kipchumba., Kiprono, Paul Chepkwony., Rajab, Mohammed Said., Kosgei, Mathew Kipchumba. Limonoids as larvicidal components against mosquito larvae (Aedes aegypti Linn.) . Zeitschrift fur naturforschung section c-a journal of biosciences, 2007, vol. 62, no. 11-12, p. 826-828.
- Lee, Won Jeong., Moon, Jae Sun., Kim, Sung In., Kim, Young Tae., Nash, Oyekanmi., Bahn, Yong-Sun., Kim, Sung Uk. Inhibition of the Calcineurin Pathway by Two Tannins, Chebulagic Acid and Chebulanin, Isolated from Harrisonia abyssinica Oliv.. JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, 2014, vol. 24, no. 10, p. 1377-1381. DOI
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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