Botanical species · safety record

Hedeoma pulegioides

The EFSA Compendium of Botanicals holds 4 constituent measurements and 2 adverse-effect records for Hedeoma pulegioides. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Hedeoma pulegioides (L.) Pers.

4Constituent measurements
2Safety records
4Cited sources
6Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 6 licensed products naming Hedeoma pulegioides as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

  • Whole plant(s)

What the records describe

Constituents measured

  • (+)-pulegone1
  • Menthone1
  • P-mentha-1,4(8)-dien-3-one1
  • Trans-isopulegone1

Plant parts

  • Unspecified4
  • Live plants1

Preparations

  • Solvent extraction1

Effect types

  • Nephrotoxicity1
  • Systemic1

Target tissues

  • Liver1
  • Urogenital: kidneys1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
(+)-pulegoneLive plantsSolvent extractionStandard Chromatographic tests (paper- thin layer- and column chromatography)Resolve DOI
MenthoneUnspecified1.4 PercentGaschromatography (GC)Resolve DOI
P-mentha-1,4(8)-dien-3-oneUnspecified1.4 PercentGaschromatography (GC)Resolve DOI
Trans-isopulegoneNo resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
NephrotoxicityUrogenital: kidneysUnspecifiedCase reportResolve DOI
SystemicLiverUnspecifiedCase reportResolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. HANDA, KL., NIGAM, IC., SMITH, DM., LEVI, L. ESSENTIAL OILS + THEIR CONSTITUENTS .23. CHEMOTAXONOMY OF GENUS MENTHA. Journal of pharmaceutical sciences, 1964, vol. 53, no. 11, p. 1407-&. DOI
  2. Wishart, DS., Jewison, T., Guo, AC., Wilson, M., Knox, C., Liu, Y., Djoumbou, Y., Mandal, R., Aziat, F., Dong, E., Bouatra, S., Sinelnikov, I., Arndt, D., Xia, J., Liu, P., Yallou, F., Bjorndahl, T., Perez-Pineiro, R., Eisner, R., Allen, F., Neveu, V., Greiner, R., Scalbert, A. (-)-trans-Isopulegone (HMDB35741).. Human metabolome database, 2012, vol. 3.0.
  3. Luyckx, V.A. Nephrotoxicity of Alternative Medicine Practice. Advances in chronic kidney disease, 2012, vol. 19, no. 3, p. 129-141. DOI
  4. SLECKMAN, BP., SHERMA, J., MINEO, LC. DETERMINATION OF PULEGONE IN H-PULEGIOIDES AND PEPPERMINT OIL BY THIN-LAYER CHROMATOGRAPHY WITH DENSITOMETRY . Journal of liquid chromatography, 1983, vol. 6, no. 7, p. 1175-1182. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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