Botanical species · safety record

Hedera helix

The EFSA Compendium of Botanicals holds 7 constituent measurements and 1 adverse-effect record for Hedera helix. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Hedera helix L.

7Constituent measurements

1Safety records

6Cited sources

87Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 87 licensed products naming Hedera helix as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Source material stated

Flowering twigs
Fresh, fully developed, non-lignified shootscollected before or at the beginning of the flowering period
Hedera helix
Herb flowering
Leaf
Leaf extract
Rameau en fleur
Shoots

What the records describe

Constituents measured

Plant parts

Preparations

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Beta-hederin	Stem / stalk	—	—	Chromatography hyphenated to element spectrometry	Resolve DOI
Saponins	Leaves	Solvent extraction	—	Unspecified	Resolve DOI
Saponins	Live plants	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Triterpene saponins	Leaves	Solvent extraction	15.69 Percent	HPLC-DAD	Resolve DOI
Triterpene saponins	Leaves	Solvent extraction	1.05 Percent	HPLC-DAD	Resolve DOI
Triterpene saponins	Aerial part of plants	—	—	—	Resolve DOI
Calcium oxalate	Aerial part of plants	—	—	Unspecified	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Not stated	Digestive	Unspecified	—	—	Case report	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Busser, C. Toxic berries, fruits and pseudo-fruits in traditional medicine and phytotherapy . Phytotherapie (paris), 2007, vol. 5, no. 1, p. 31-36. DOI
Yu, Miao., Shin, Young June., Kim, Nanyoung., Yoo, Guijae., Park, SeonJu., Kim, Seung Hyun. Determination of Saponins and Flavonoids in Ivy Leaf Extracts Using HPLC-DAD . Journal of chromatographic science, 2015, vol. 53, no. 4, p. 478-483. DOI
Himmelsbach, Markus., Weth, Agnes., Boehme, Christine., Schwarz, Martin., Braeunig, Peter., Baumgartner, Werner. The plant hopper Issus coleoptratus can detoxify phloem sap saponins including the degradation of the terpene core . Biology open, 2016, vol. 5, no. 3, p. 252-255. DOI
Tutuncu Konyar, Sevil., Ozturk, Necla., Dane, Feruzan. Occurrence, types and distribution of calcium oxalate crystals in leaves and stems of some species of poisonous plants. Botanical studies, 2014, vol. 55, no. 1, p. 1-9.
ELIAS, R., DEMEO, M., VIDALOLLIVIER, E., LAGET, M., BALANSARD, G., DUMENIL, G. ANTIMUTAGENIC ACTIVITY OF SOME SAPONINS ISOLATED FROM CALENDULA-OFFICINALIS L, CALENDULA-ARVENSIS L AND HEDERA-HELIX L . Mutagenesis, 1990, vol. 5, no. 4, p. 327-331. DOI
Walthelm, U., Dittrich, K., Gelbrich, G., Schopke, T. Effects of saponins on the water solubility of different model compounds. Planta medica, 2001, vol. 67, no. 1, p. 49-54. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature