Heliotropium indicum

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

1. Kyei, S., Koffuor, G.A., Ramkissoon, P., Asante, D.-B. Oral and ocular safety profile of whole plant aqueous extract of Heliotropium indicum L. In rodents. Research journal of medicinal plant, 2015, vol. 9, no. 7, p. 321-330. DOI
2. Zhou, Jue., Ouedraogo, Moustapha., Qu, Fan., Duez, Pierre. Potential Genotoxicity of Traditional Chinese Medicinal Plants and Phytochemicals: An Overview. PHYTOTHERAPY RESEARCH, 2013, vol. 27, no. 12, p. 1745-1755. DOI
3. Biradi, Mahesh., Hullatti, Kirankumar. Screening of Indian medicinal plants for cytotoxic activity by brine shrimp lethality (BSL) assay and evaluation of their total phenolic content. Drug development and therapeutics, 2014, vol. 5, no. 2, p. 139-144.
4. van de Schans, M.G.M., Blokland, M.H., Zoontjes, P.W., Mulder, P.P.J., Nielen, M.W.F. Multiple heart-cutting two dimensional liquid chromatography quadrupole time-of-flight mass spectrometry of pyrrolizidine alkaloids. Journal of chromatography a, 2017, vol. 1503, p. 38-48. DOI
5. Dolui, A. K., Debnath, Manabendra., De, B., Kumar, Atul. Reproductive activities of Heliotropium indicum isolate against Helopeltis theivora and toxicity evaluation in mice . Journal of environmental biology, 2012, vol. 33, no. 3, p. 603-607.
6. van Weeren, PR., Morales, JA., Rodriguez, LL., Cedeno, H., Villalobos, J., Poveda, LJ. Mortality supposedly due to intoxication by pyrrolizidine alkaloids from Heliotropium indicum in a horse population in Costa Rica: A case report . Veterinary quarterly, 1999, vol. 21, no. 2, p. 59-62.
7. Afolabi, F., Afolabi, O. J. Phytochemical constituents of some medicinal plants in South West, Nigeria. Iosr journal of applied chemistry, 2013, vol. 4, no. 1), 76-7, p. 3 pp.
8. Owolabi, M A., Oribayo, O O., Ukpo, G E., Mbaka, G O., Akindehin, O E. A 5-month toxicity study of the ethanol extract of the leaves of Heliotropium indicum in Sprague Dawley rats after oral administration. . Nigerian quarterly journal of hospital medicine, 2015, vol. 25, no. 3, p. 184-92.
9. Schoental, Regina. Toxicology and carcinogenic action of pyrrolizidine alkaloids. Cancer research, 1968, vol. 28, no. 11, p. 2237-46.
10. Boye, A., Koffuor, G. A., Amoateng, P., Ameyaw, E. O., Abaitey, A. K. Analgesic Activity and Safety Assessment of Heliotropium indicum Linn. (Boraginaceae) in Rodents . International journal of pharmacology, 2012, vol. 8, no. 2, p. 91-100. DOI
11. Froelich, Cordula., Ober, Dietrich., Hartmann, Thomas. Tissue distribution, core blosynthesis and diversification of pyrrolizidine alkaloids of the lycopsamine type in three Boraginaceae species . Phytochemistry, 2007, vol. 68, no. 7, p. 1026-1037. DOI

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