Botanical species · safety record

Hemidesmus indicus

The EFSA Compendium of Botanicals holds 7 constituent measurements, 1 adverse-effect record and 1 genotoxicity assay for Hemidesmus indicus. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Hemidesmus indicus (L.) R. Br. ex Schult.

7Constituent measurements

2Safety records

4Cited sources

35Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 35 licensed products naming Hemidesmus indicus as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Source material stated

Aged bark
Root
Root extract

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Coumarins	Roots and other underground parts	Solvent extraction	—	Phytochemical screening	Resolve DOI
Pregnane derivatives	Stem / stalk	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Alkaloids	Roots and other underground parts	Solvent extraction	≥ 0.35 Microgram/gram	Phytochemical screening	No resolvable identifier
Alkaloids	Roots and other underground parts	Solvent extraction	≤ 0.75 Microgram/gram	Phytochemical screening	No resolvable identifier
Alkaloids	Stem / stalk	—	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	No resolvable identifier
Saponins	Roots and other underground parts	Solvent extraction	≥ 2.82 Microgram/gram	Phytochemical screening	No resolvable identifier
Saponins	Roots and other underground parts	Solvent extraction	≤ 3.2 Microgram/gram	Phytochemical screening	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Hepatotoxicity	Liver	Stem / stalk	—	Rat (as animal)	Short-term toxicity	No resolvable identifier

Genotoxicity testing

Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.

Outcome	Endpoint	Test	Tested organism	Metabolic activation	Source
Positive	chromosome aberration	chromosome aberration assay	Human (as organism)	No data	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Ananthi, R., Chandra, N., Santhiya, S. T., Ramesh, A. Genotoxic and antigenotoxic effects of Hemidesmus indicus R. Br. root extract in cultured lymphocytes. JOURNAL OF ETHNOPHARMACOLOGY, 2010, vol. 127, no. 2, p. 558-560. DOI
Arseculeratne S N., Gunatilaka A A., Panabokke R G. Studies of medicinal plants of Sri Lanka. Part 14: Toxicity of some traditional medicinal herbs. Journal of ethnopharmacology, 1985, p. 323-335.
Rekha, S., Parvathi, A. Evaluation of phytochemical constituents of the roots of licorice, Indian ginseng, Indian madder and Indian Sarsaparilla. International Journal of Pharma and Bio Sciences, 2012, vol. 3, no. 2, p. 357-362.
Deepak, D., Srivastava, S., Khare, A. Pregnane glycosides from Hemidesmus indicus. PHYTOCHEMISTRY, 1997, vol. 44, no. 1, p. 145-151. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature