Botanical species · safety record

Heracleum mantegazzianum

The EFSA Compendium of Botanicals holds 12 constituent measurements for Heracleum mantegazzianum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Heracleum mantegazzianum Sommier & Levier

12Constituent measurements
0Safety records
4Cited sources
0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

  • Coumarins2
  • Angelicin1
  • Bergapten1
  • Furanocoumarins1
  • Imperatorin1
  • Isopimpinellin1
  • Limettin1
  • Methoxsalen1
  • Phellopterin1
  • Pimpinellin1

Plant parts

  • Fruit unspecified9
  • Seed2
  • Live plants1

Preparations

  • Solvent extraction12

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
AngelicinFruit unspecifiedSolvent extraction—High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
BergaptenFruit unspecifiedSolvent extraction—High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
CoumarinsSeedSolvent extraction—GC-MSResolve DOI
CoumarinsFruit unspecifiedSolvent extraction—High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
FuranocoumarinsSeedSolvent extraction—GC-MSResolve DOI
ImperatorinFruit unspecifiedSolvent extraction—High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
IsopimpinellinFruit unspecifiedSolvent extraction—High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
LimettinFruit unspecifiedSolvent extraction—High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
MethoxsalenFruit unspecifiedSolvent extraction—High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
PhellopterinFruit unspecifiedSolvent extraction—High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
PimpinellinFruit unspecifiedSolvent extraction—High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
PsoralenLive plantsSolvent extraction——Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. KNUDSEN, EA. SEASONAL-VARIATIONS IN THE CONTENT OF PHOTO-TOXIC COMPOUNDS IN GIANT HOGWEED . Contact dermatitis, 1983, vol. 9, no. 4, p. 281-284. DOI
  2. Jakubska-Busse, A., Sliwinski, M., Kobylka, M. IDENTIFICATION OF BIOACTIVE COMPONENTS OF ESSENTIAL OILS IN HERACLEUM SOSNOWSKYI AND HERACLEUM MANTEGAZZIANUM (APIACEAE) . Archives of biological sciences, 2013, vol. 65, no. 3, p. 877-883. DOI
  3. Walasek, Magdalena., Grzegorczyk, Agnieszka., Malm, Anna., Skalicka-Wozniak, Krystyna. Bioactivity-guided isolation of antimicrobial coumarins from Heracleum mantegazzianum Sommier & Levier (Apiaceae) fruits by high-performance counter-current chromatography . Food chemistry, 2015, vol. 186, p. 133-138. DOI
  4. Glowniak, K., Mroczek, T., Zabza, A., Cierpicki, T. Isolation and structure elucidation of 5,7-disubstituted simple coumarins in the fruits of Heracleum mantegazzianum . Pharmaceutical biology, 2000, vol. 38, no. 4, p. 308-312. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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