Botanical species · safety record
Herniaria glabra
The EFSA Compendium of Botanicals holds 5 constituent measurements and 1 adverse-effect record for Herniaria glabra. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Herniaria glabra L.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 11 licensed products naming Herniaria glabra as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Extract types on licence
Source material stated
What the records describe
Constituents measured
- Triterpene saponins2
- Dillapiole1
- Estragole1
- Pentacyclic triterpene saponins1
Plant parts
- Aerial part of plants3
- Unspecified2
- Live plants1
Preparations
- Essential oil2
- Solvent extraction2
- Drying (dehydration)1
- Fresh1
Effect types
- Systemic1
Target tissues
- Liver1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Pentacyclic triterpene saponins | Aerial part of plants | Solvent extraction | — | GC-MS | Resolve DOI |
| Triterpene saponins | Aerial part of plants | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Dillapiole | Unspecified | Essential oil | — | GC-MS | No resolvable identifier |
| Estragole | Unspecified | Essential oil | — | GC-MS | No resolvable identifier |
| Triterpene saponins | Aerial part of plants | Fresh | 15 Percent | — | No resolvable identifier |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Systemic | Liver | Live plants | Drying (dehydration) | Rat (as animal) | Subchronic | Resolve DOI |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Rhiouani, Hamid., El-Hilaly, Jaouad., Israili, Zafar H., Lyoussi, Badiaa. Acute and sub-chronic toxicity of an aqueous extract of the leaves of Herniaria glabra in rodents . Journal of ethnopharmacology, 2008, vol. 118, no. 3, p. 378-386. DOI
- Khakim, El Mabruki., Klemper, A. V., Kaukhova, I. E., Sorokin, V. V. ESTABLISHMENT OF RUPTUREWORT (HERNIARIA GIABRA) HERB IDENTITY CHARACTERESTICS AND QUALITY INDICES . Farmatsiya (moscow), 2014, no. 6, p. 21-24.
- Hethelyi, E. B., Galambosi, B., Szarka, S., Lemberkovics, E., Szoke, E. Phytochemical investigation of medicinal and culinary herbs. Acta agronomica hungarica, 2012, vol. 60, no. 3, p. 201-207.
- SCHRODER, H., SCHUBERTZSILAVECZ, M., REZNICEK, G., CART, J., JURENITSCH, J., HASLINGER, E. A TRITERPENE SAPONIN FROM HERNIARIA-GLABRA. Phytochemistry, 1993, vol. 34, no. 6, p. 1609-1613. DOI
- Freiler, M., Reznicek, G., Jorenitsch, J., Kubelka, W., Schmidt, W., SchubertZsilavecz, M., Haslinger, E., Reiner, J. New triterpene saponins from Herniaria glabra. Helvetica chimica acta, 1996, vol. 79, no. 2, p. 385-390. DOI
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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