Botanical species · safety record

Hibiscus sabdariffa

The EFSA Compendium of Botanicals holds 14 constituent measurements and 8 adverse-effect records for Hibiscus sabdariffa. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Hibiscus sabdariffa L.

14Constituent measurements

8Safety records

10Cited sources

164Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 164 licensed products naming Hibiscus sabdariffa as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Dry
Fresh

Source material stated

Flower
Flower calyces
Flowers
Leaf
Leaf/Leaves
New material
Sepal
Whole plant

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
1,8-cineole	—	Solvent extraction	—	GC-MS	No resolvable identifier
Alkaloids	Seed	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Anthraquinones	Seed	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Benzaldehyde	—	Solvent extraction	—	GC-MS	No resolvable identifier
Camphor	—	Solvent extraction	—	GC-MS	No resolvable identifier
Cardenolides	Seed	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Cardiac glycosides	Seed	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Cyanide	Leaves	Fresh	63.98 Milligram/kilogram	—	No resolvable identifier
Furfural	—	Solvent extraction	—	GC-MS	No resolvable identifier
Nonanal	—	Solvent extraction	—	GC-MS	No resolvable identifier
Oxalates	Leaves	Fresh	4.35 Gram/kilogram	Distillation-titrimetry (modified Monier-William method)	No resolvable identifier
Phlobotannins	Seed	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Saponins	Seed	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Tannins	Seed	Solvent extraction	—	Phytochemical screening	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Digestive	Digestive	Fruit unspecified	Solvent extraction	Saccharomyces cerevisiae (as organism)	In vitro	Resolve DOI
Digestive	Digestive: pancreas	Flower	Solvent extraction	Pig (as animal)	In vitro	Resolve DOI
Digestive	Digestive	Flower	Solvent extraction	Rat (as animal)	In vitro	Resolve DOI
Other toxicities	Digestive	Unspecified	Solvent extraction	Rat (as animal)	Chronic/long term toxicity	Resolve DOI
Other toxicities	Liver	Fruit unspecified	Solvent extraction	Rat (as animal)	Short-term toxicity	Resolve DOI
Reproductive	Testes	Unspecified	Solvent extraction	House mouse (as animal)	Reproduction toxicity	Resolve DOI
Endocrine	—	Seed	Solvent extraction	Rat (as animal)	Short-term toxicity	No resolvable identifier
Systemic	—	Flower	Solvent extraction	Rat (as animal)	Subchronic	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Shadhan, Raheem Mohssin., Bohari, Siti Pauliena Mohd. Effects of Hibiscus sabdariffa Linn. fruit extracts on alpha-glucosidase enzyme, glucose diffusion and wound healing activities . Asian pacific journal of tropical biomedicine, 2017, vol. 7, no. 5, p. 466-472. DOI
Gaya, Ibrahim Bako., Abdulhalim Mohammad, Okasha Mohammad., Suleiman, Abubakar Mujtaba., Maje, Mohammad Idris., Adekunle, Adebayo Buraimoh. Toxicological and lactogenic studies on the seeds of Hibiscus sabdariffa linn (malvaceae) extract on serum prolactin levels of albino Wistar rats. Internet journal of endocrinology, 2009, vol. 5, no. 2, p. No pp given.
Mahmoud, Yomna Ibrahim. Effect of extract of Hibiscus on the ultrastructure of the testis in adult mice . Acta histochemica, 2012, vol. 114, no. 4, p. 342-348. DOI
Musa, Amanabo., Ogbadoyi, Emmanuel O. Levels of phytotoxins and nutrients in Hibiscus sabdariffa as influenced by freezing storage. British journal of applied science & technology, 2013, vol. 3, no. 4, p. 799-812.
Sireeratawong, Seewaboon., Itharat, Arunporn., Khonsung, Parirat., Lertprasertsuke, Nirush., Jaijoy, Kanjana. TOXICITY STUDIES OF THE WATER EXTRACT FROM THE CALYCES OF HIBISCUS SABDARIFFA L. IN RATS . African journal of traditional complementary and alternative medicines, 2013, vol. 10, no. 4, p. 122-127. DOI
Akindahunsi, AA., Olaleye, MT. Toxicological investigation of aqueous-methanolic extract of the calyces of Hibiscus sabdariffia L. . Journal of ethnopharmacology, 2003, vol. 89, no. 1, p. 161-164. DOI
Adisakwattana, Sirichai., Ruengsamran, Thanyachanok., Kampa, Patcharaporn., Sompong, Weerachat. In vitro inhibitory effects of plant-based foods and their combinations on intestinal alpha-glucosidase and pancreatic alpha-amylase . Bmc complementary and alternative medicine, 2012, vol. 12. DOI
Ali, Badreldin H., Al-Lawati, Intisar., Beegam, Sumyia., Ziada, Amal., Al salam, Suhail., Nemmar, Abderrahim., Blunden, Gerald. Effect of Hibiscus sabdariffa and its Anthocyanins on some Reproductive Aspects in Rats . Natural product communications, 2012, vol. 7, no. 1, p. 41-44.
CHOi, SUNG HEE. Volatile Aroma Components of Hibiscus Herb Tea. Journal of the korean tea society, 2008, vol. 14, no. 1, p. 195-204.
Fakeye, Titilayo. Toxicity and immunomodulatory activity of fractions of Hibiscus sabdariffa Linn (family Malvaceae) in animal models . African journal of traditional complementary and alternative medicines, 2008, vol. 5, no. 4, p. 394-398.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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