Botanical species · safety record

Holoptelea integrifolia

The EFSA Compendium of Botanicals holds 5 constituent measurements and 3 adverse-effect records for Holoptelea integrifolia. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Holoptelea integrifolia (Roxb.) Planch.

5Constituent measurements

3Safety records

4Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Calcium oxalate	Roots and other underground parts	—	—	Microscopic detection	Resolve DOI
Coumarins	Bark	Solvent extraction	—	LC-MS/MS	Resolve DOI
Alkaloids	Leaves	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Saponins	Leaves	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Tannins	Leaves	Solvent extraction	—	Phytochemical screening	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Digestive	Liver	Bark	Solvent extraction	Rat (as animal)	Short-term toxicity	No resolvable identifier
Digestive	Liver	Bark	Solvent extraction	Rat (as animal)	Short-term toxicity	No resolvable identifier
Nephrotoxicity	Urogenital: kidneys	Bark	Solvent extraction	Rat (as animal)	Short-term toxicity	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Kumar, Dinesh., Kumar, Karunesh., Kumar, Sunil., Kumar, Tarun., Kumar, Ajay., Prakash, Om. Pharmacognostic evaluation of leaf and root bark of Holoptelea integrifolia Roxb. . Asian pacific journal of tropical biomedicine, 2012, vol. 2, no. 3, p. 169-175. DOI
Rizwani, Ghazala Hafeez., Mahmud, Shaukat., Shareef, Huma., Perveen, Rehana., Ahmed, Maryam. Analgesic activity of various extracts of Holoptelea integrifolia (Roxb.) Planch leaves . Pakistan journal of pharmaceutical sciences, 2012, vol. 25, no. 3, p. 629-632.
Subash, Arun Koorappally., Augustine, Anu. Hypolipidaemic Effects of Methanol Extract of Holoptelea integrifolia (Roxb.) Planchon Bark in Diet-Induced Obese Rats. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 2013, vol. 169, no. 2, p. 546-553. DOI
Kumar, D., Patil, P., Hegde, H.V., Roy, S., Kholkute, S. Safety evaluation of petroleum ether, Acetone and hydroalcoholic extracts of holoptelea integrifolia (ROXB.) Planch. Bark by oral administration in wistar rats. Asian Journal of Pharmaceutical and Clinical Research, 2015, vol. 8, no. 2, p. 185-189.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature