Botanical species · safety record

Houttuynia cordata

The EFSA Compendium of Botanicals holds 6 constituent measurements and 1 adverse-effect record for Houttuynia cordata. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Houttuynia cordata (Thunb.)

6Constituent measurements

1Safety records

3Cited sources

102Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 102 licensed products naming Houttuynia cordata as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Source material stated

Aerial parts
Dried aerial part(s)
Herb
Herb top
Leaf
Whole plant
Whole plant(s)

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Aristolactam	Aerial part of plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Cepharadione b	Aerial part of plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Norcepharadione b	Aerial part of plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Piperolactam a	Aerial part of plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Splendidine	Aerial part of plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Myrcene	Unspecified	Essential oil	1.64 Percent	GC-MS	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Nephrotoxicity	Urogenital: kidneys	Leaves	Solvent extraction	Rat (as animal)	Subchronic	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Yoshino, H., Imai, N., Nabae, K., Doi, Y., Tamano, S., Ogawa, K., Shirai, T. Thirteen-week oral toxicity study of Dokudami extract (Houttuynia cordata Thunb.) in F344/DuCrj rats. Journal of toxicologic pathology, 2006, vol. 18, no. 4, p. 175-182. DOI
Ch, Muhammad Ishtiaq., Wen, Yang F., Cheng, YiYu. Gas chromatographic/mass spectrometric analysis of the essential oil of Houttuynia cordata Thunb by using on-column methylation with tetramethylammonium acetate . Journal of aoac international, 2007, vol. 90, no. 1, p. 60-67.
Kim, SK., Ryu, SY., No, J., Choi, SU., Kim, YS. Cytotoxic alkaloids from Houttuynia cordata. ARCHIVES OF PHARMACAL RESEARCH, 2001, vol. 24, no. 6, p. 518-521. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature