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Botanical species · safety record

Huperzia selago

The EFSA Compendium of Botanicals holds 9 constituent measurements for Huperzia selago. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Huperzia selago (L.) Bernh. ex Schrank & Mart.

9Constituent measurements
0Safety records
6Cited sources
0Licensed products (Canada)

Also recorded as

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

  • Huperzine a4
  • Lycopodine3
  • Alkaloids2

Plant parts

  • Aerial part of plants8
  • Unspecified1

Preparations

  • Solvent extraction8

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
AlkaloidsAerial part of plantsSolvent extraction—High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)Resolve DOI
AlkaloidsAerial part of plantsSolvent extraction—Nuclear Magnetic Resonance (NMR)Resolve DOI
Huperzine aAerial part of plantsSolvent extraction—Nuclear Magnetic Resonance (NMR)Resolve DOI
Huperzine aAerial part of plantsSolvent extraction≥ 0.44 Milligram/gramHPLC-UVResolve DOI
Huperzine aAerial part of plantsSolvent extraction≤ 1.59 Milligram/gramHPLC-UVResolve DOI
LycopodineUnspecified——UnspecifiedResolve DOI
LycopodineAerial part of plantsSolvent extraction—HPLC-MS/MSResolve DOI
Huperzine aAerial part of plantsSolvent extraction—HPLC-MS/MSNo resolvable identifier
LycopodineAerial part of plantsSolvent extraction—HPLC-MS/MSNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Maonian Xu., Finnur Freyr Eiriksson., Margret Thorsteinsdottir., Starri Heidmarsson., Sesselja Omarsdottir., Elin Soffia Olafsdottir. Alkaloid fingerprinting resolves Huperzia selago genotypes in Iceland. Biochemical systematics and ecology, 2019, vol. 83, p. 77-82.
  2. Johansen, Kenneth T., Ebild, Sarah J., Christensen, S. Brogger., Godejohann, Markus., Jaroszewski, Jerzy W. Alkaloid analysis by high-performance liquid chromatography-solid phase extraction-nuclear magnetic resonance: New strategies going beyond the standard . Journal of chromatography a, 2012, vol. 1270, p. 171-177. DOI
  3. Staerk, D., Larsen, J., Larsen, LA., Olafsdottir, ES., Witt, M., Jaroszewski, JW. Selagoline, a new alkaloid from Huperzia selago. Natural product research, 2004, vol. 18, no. 3, p. 197-203. DOI
  4. Szypula, W. J., Kiss, A. K., Pietrosiuk, A., Swist, M., Danikiewicz, W., Olszowska, O. Determination of Huperzine A in Huperzia selago Plants from Wild Population and Obtained in In Vitro Culture by High-Performance Liquid Chromatography Using a Chaotropic Mobile Phase . Acta chromatographica, 2011, vol. 23, no. 2, p. 339-352. DOI
  5. Ma, X., Tan, C., Zhu, D., Gang, D.R. A survey of potential huperzine A natural resources in China: The Huperziaceae. Journal of ethnopharmacology, 2006, vol. 104, no. 1-2, p. 54-67. DOI
  6. Czapski, Grzegorz A., Szypula, Wojciech., Kudlik, Magdalena., Wilenska, Beata., Kania, Magdalena., Danikiewicz, Witold., Adamczyk, Agata. Assessment of antioxidative activity of alkaloids from Huperzia selago and Diphasiastrum complanatum using in vitro systems . Folia neuropathologica, 2014, vol. 52, no. 4, p. 394-406. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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