Botanical species · safety record

Hyoscyamus muticus

The EFSA Compendium of Botanicals holds 22 constituent measurements and 1 adverse-effect record for Hyoscyamus muticus. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Hyoscyamus muticus L.

22Constituent measurements

1Safety records

5Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Tropane alkaloids	Aerial part of plants	Solvent extraction	—	Unspecified	Resolve DOI
Alkaloids	Flower	Solvent extraction	1.25 Percent	GC-MS	No resolvable identifier
Alkaloids	Fruit peel	Solvent extraction	1.02 Percent	GC-MS	No resolvable identifier
Alkaloids	Leaves	Solvent extraction	1.9 Percent	GC-MS	No resolvable identifier
Alkaloids	Roots and other underground parts	Solvent extraction	0.72 Percent	GC-MS	No resolvable identifier
Alkaloids	Stem / stalk	Solvent extraction	1.59 Percent	GC-MS	No resolvable identifier
Apoatropine	Live plants	Solvent extraction	≤ 11.65 Percent	GC-MS	No resolvable identifier
Apoatropine	Live plants	Solvent extraction	≥ 2.55 Percent	GC-MS	No resolvable identifier
Atropine	Seed	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Atropine	Live plants	Solvent extraction	≤ 0.71 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Atropine	Live plants	Solvent extraction	≥ 0.32 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Erucic acid	Roots and other underground parts	Solvent extraction	—	GC-MS	No resolvable identifier
Hygrine	Roots and other underground parts	Solvent extraction	—	GC-MS	No resolvable identifier
Hyoscyamine	Live plants	Solvent extraction	≤ 96.43 Percent	GC-MS	No resolvable identifier
Hyoscyamine	Live plants	Solvent extraction	≥ 80.52 Percent	GC-MS	No resolvable identifier
Scopolamine	Live plants	Solvent extraction	≤ 0.04 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Scopolamine	Live plants	Solvent extraction	≥ 0.002 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Scopolamine	Live plants	Solvent extraction	≤ 2.8 Percent	GC-MS	No resolvable identifier
Scopolamine	Live plants	Solvent extraction	≥ 1.02 Percent	GC-MS	No resolvable identifier
Scopolamine	Seed	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Scopoletin	Leaves	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Tropane alkaloids	Roots and other underground parts	Solvent extraction	—	GC-MS	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Neurotoxicity	Neurologic: central nervous system	Aerial part of plants	Solvent extraction	Human (as organism)	Case report	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

El-Shazly, A., Tei, A., Witte, L., El-Domiaty, M., Wink, M. Tropane alkaloids of Hyoscyamus boveanus, H-desertorum, H-muticus and H-albus from Egypt . Zeitschrift fur naturforschung c-a journal of biosciences, 1997, vol. 52, no. 11-12, p. 729-739.
Dawidar, Abdel-Aziz M., Abdel-Mogib, Mamdouh., El-Naggar, Mahmoud E., Mostafa, Mohamed E. Acaricidal activity and chemical constituents of Hyoscyamus muticus against Tetranychus urticae Koch. Revista Latinoamericana de Quimica, 2009, p. 45-55.
Oumerzouk, Jawad., Hssaini, Yahya., Boulahri, Tarik., Semlali, Adnane., El Jouehari, Abdelhafid., Bourazza, Ahmed. A massive poisoning by Hyoscyamus muticus, complicated by axonal sensorimotor polyneuropathy . Presse medicale, 2013, vol. 42, no. 3, p. 354-355. DOI
Mandal, S., Naqvi, A. A., Thakur, R. S. Simultaneous determination of atropine and scopolamine in plants by mixed-column high performance liquid chromatography. Phytochemical Analysis, 1991, p. 208-210.
Ashraf, Muhammad., Alam, Mahbub., Dara, M. Shahid Tauqeer. Nonaqueous determination of scopolamine and atropine in Hyoscyamus and Datura seeds. Journal of pharmacy (lahore), 1985, p. 55-58.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature