Botanical species · safety record
Hyoscyamus niger
The EFSA Compendium of Botanicals holds 4 constituent measurements and 1 adverse-effect record for Hyoscyamus niger. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Hyoscyamus niger L.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 68 licensed products naming Hyoscyamus niger as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Source material stated
What the records describe
Constituents measured
- Alkaloids1
- Lignans1
- Saponins1
- Tropane alkaloids1
Plant parts
- Seed3
- Live plants1
Preparations
- Solvent extraction4
Effect types
- Neurotoxicity1
Target tissues
- Neurologic: central nervous system1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Alkaloids | Seed | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Lignans | Seed | Solvent extraction | — | Unspecified | No resolvable identifier |
| Saponins | Seed | Solvent extraction | — | Unspecified | No resolvable identifier |
| Tropane alkaloids | Live plants | Solvent extraction | — | Unspecified | No resolvable identifier |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Neurotoxicity | Neurologic: central nervous system | — | — | Human (as organism) | Case report | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Alizadeh, Anahita., Moshiri, Mohammad., Alizadeh, Javad., Balali-Mood, Mahdi. Black henbane and its toxicity - a descriptive review.. Avicenna journal of phytomedicine, 2014, vol. 4, no. 5, p. 297-311.
- Ma, CY., Liu, WK., Che, CT. Lignanamides and nonalkaloidal components of Hyoscyamus niger seeds. Journal of natural products, 2002, vol. 65, no. 2, p. 206-209. DOI
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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