Botanical species · safety record

Hyssopus officinalis

The EFSA Compendium of Botanicals holds 21 constituent measurements and 1 adverse-effect record for Hyssopus officinalis. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Hyssopus officinalis L.

21Constituent measurements

1Safety records

5Cited sources

194Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 194 licensed products naming Hyssopus officinalis as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Dry
Extract Type TBA
Fresh
fluid
solid

Source material stated

Aerial parts
Dried leaf
Dried leaves
Dried leaves and flowering tops
Flower
Flowering top(s)
Flowering tops
Grass(es)

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
1,8-cineole	Leaves	Essential oil	2.99 Percent	GC-MS	Resolve DOI
1,8-cineole	Aerial part of plants	Essential oil	≤ 8 Percent	GC-FID	Resolve DOI
1,8-cineole	Aerial part of plants	Essential oil	≥ 2.9 Percent	GC-FID	Resolve DOI
Coumarin	Leaves	Solvent extraction	2.7 Microgram/100 gram	HPLC-UV	Resolve DOI
Esculetin	Leaves	Solvent extraction	≤ 17.6 Microgram/100 gram	HPLC-UV	Resolve DOI
Esculetin	Leaves	Solvent extraction	≥ 1.9 Microgram/100 gram	HPLC-UV	Resolve DOI
Myrcene	Leaves	Essential oil	2.92 Percent	GC-MS	Resolve DOI
Myrcene	Aerial part of plants	Essential oil	≤ 1.3 Percent	GC-FID	Resolve DOI
Myrcene	Aerial part of plants	Essential oil	≥ 0.5 Percent	GC-FID	Resolve DOI
Phenanthrenes	Aerial part of plants	Essential oil	≤ 1.9 Percent	GC-FID	Resolve DOI
Pinocarvone	Aerial part of plants	Essential oil	≥ 5.5 Percent	GC-FID	Resolve DOI
Pinocarvone	Aerial part of plants	Essential oil	≤ 24.9 Percent	GC-FID	Resolve DOI
Pinocarvone	Leaves	Essential oil	29.17 Percent	GC-MS	Resolve DOI
(+)-pulegone	Aerial part of plants	Essential oil	≤ 2.93 Percent	GC-MS	No resolvable identifier
(-)-pinocamphone	Aerial part of plants	Essential oil	≤ 53.73 Percent	GC-MS	No resolvable identifier
(-)-pinocamphone	Aerial part of plants	Essential oil	≥ 35.49 Percent	GC-MS	No resolvable identifier
Camphor	Aerial part of plants	Essential oil	≤ 3.86 Percent	GC-MS	No resolvable identifier
Iso-pinocamphone	Aerial part of plants	Essential oil	≤ 44.43 Percent	GC-MS	No resolvable identifier
Iso-pinocamphone	Aerial part of plants	Essential oil	≥ 4.66 Percent	GC-MS	No resolvable identifier
Methyleugenol	Aerial part of plants	Essential oil	≥ 0.14 Percent	GC-MS	No resolvable identifier
Methyleugenol	Aerial part of plants	Essential oil	≤ 1.16 Percent	GC-MS	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Neurotoxicity	Brain	Unspecified	—	—	Not reported	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Kotyuk, L. A. Hyssop composition depending on age and plants development phases. Biotechnologia acta, 2015, vol. 8, no. 5, p. 55-63.
Bajerova, Petra., Adam, Martin., Bajer, Tomas., Ventura, Karel. Comparison of various techniques for the extraction and determination of antioxidants in plants. JOURNAL OF SEPARATION SCIENCE, 2014, vol. 37, no. 7, p. 835-844. DOI
Figueredo, Guilles., Ozcan, Mehmet Musa., Chalchat, Jean Claude., Bagci, Yavuz., Chalard, Pierre. Chemical Composition of Essential Oil of Hyssopus officinalis L. and Origanum acutidens . Journal of essential oil bearing plants, 2012, vol. 15, no. 2, p. 300-306. DOI
Pandey, Vineeta., Verma, Ram S., Chauhan, Amit., Tiwari, Rakesh. Compositional variation in the leaf, flower and stem essential oils of Hyssop (Hyssopus officinalis L.) from Western-Himalaya . Journal of herbal medicine, 2014, vol. 4, no. 2, p. 89-95. DOI
Burkhard, PR., Burkhardt, K., Haenggeli, CA., Landis, T. Plant-induced seizures: reappearance of an old problem. Journal of neurology, 1999, vol. 246, no. 8, p. 667-670. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature