Botanical species · safety record

Illicium verum

The EFSA Compendium of Botanicals holds 4 constituent measurements and 2 adverse-effect records for Illicium verum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Illicium verum Hook.f.

4Constituent measurements

2Safety records

5Cited sources

57Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 57 licensed products naming Illicium verum as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Source material stated

Branch(es)
Flower
Fruit
Fruit oil
Leaf
Seed
Seed(s)
Steam distillation from fresh branch and leaf or ripe fruit

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Estragole	Fruit unspecified	Essential oil	6.58 Percent	GC-FID-MS	Resolve DOI
Estragole	Fruit unspecified	Essential oil	≤ 6 Percent	Unspecified	Resolve DOI
Estragole	Fruit unspecified	Essential oil	≥ 5 Percent	Unspecified	Resolve DOI
Phenylpropanoids	Fruit unspecified	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Digestive	Neurologic	Seed	Solvent extraction	Human (as organism)	Acute toxicity	No resolvable identifier
Neurotoxicity	Neurologic: central nervous system	Fruit unspecified	Solvent extraction	House mouse (as animal)	Acute toxicity	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Nakamura, T., Okuyama, E., Yamazaki, M. Neurotropic components from star anise (Illicium verum Hook fil). Chemical & pharmaceutical bulletin, 1996, vol. 44, no. 10, p. 1908-1914.
Mattos Navarro, Pablo., Cordero Lobat�n, Augusto., Bartos Miklos, Andr�s. Intoxicaci�n por an�s estrellado en un lactante menor. Revista de la sociedad boliviana de pediatr�a, 2007, vol. 46, no. 2, p. 105-107.
Lee, SW., Li, G., Lee, KS., Jung, JS., Xu, ML., Seo, CS., Chang, HW., Kim, SK., Song, DK., Son, JK. Preventive agents against sepsis and new phenylpropanoid glucosides from the fruits of Illicium verum . Planta medica, 2003, vol. 69, no. 9, p. 861-864.
Rolli, Enrico., Marieschi, Matteo., Maietti, Silvia., Sacchetti, Gianni., Bruni, Renato. Comparative phytotoxicity of 25 essential oils on pre- and post-emergence development of Solanum lycopersicum L.: A multivariate approach . Industrial crops and products, 2014, vol. 60, p. 280-290. DOI
De Vincenzi, M., Silano, M., Maialetti, F., Scazzocchio, B. Constituents of aromatic plants: II. Estragole. FITOTERAPIA, 2000, vol. 71, no. 6, p. 725-729. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature