Botanical species · safety record

Isatis tinctoria

The EFSA Compendium of Botanicals holds 5 constituent measurements for Isatis tinctoria. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Isatis tinctoria L.

5Constituent measurements

0Safety records

4Cited sources

284Licensed products (Canada)

Also recorded as

Isatis indigotica Fortune ex Lindl.

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 284 licensed products naming Isatis tinctoria as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Dry
Extract Type TBA
Fresh
decoction

Source material stated

Dried pigment from leaf or stem
Dried root(s)
Isatis tinctoria - Root
Leaf
Leaf and stem
New material
Root
Root and rhizome

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Indole alkaloids	Roots and other underground parts	Solvent extraction	—	HPLC with standard detection methods	Resolve DOI
Lariciresinol	Roots and other underground parts	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Glucoibervirin	Leaves	Solvent extraction	0.824 Millimole/kilogram	HPLC-UV	No resolvable identifier
Salicylic acid	Roots and other underground parts	—	—	—	No resolvable identifier
Sum of glucosinolates	Roots and other underground parts	Solvent extraction	49.973 Millimole/kilogram	HPLC-UV	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Li, Jing., Liu, Yunhai., Tang, Jie., Xie, Wei. Anti-endotoxic effects of salicylic acid from Radix isatidis. Zhongguo yiyuan yaoxue zazhi, 2007, vol. 27, no. 10, p. 1349-1352.
Yang, Liguo., Wang, Guan., Wang, Meng., Jiang, Hongmei., Chen, Lixia., Zhao, Feng., Qiu, Feng. Indole alkaloids from the roots of Isatis indigotica and their inhibitory effects on nitric oxide production . Fitoterapia, 2014, vol. 95, p. 175-181. DOI
Hu, Ye., Liang, Hao., Yuan, Qipeng., Hong, Yuancheng. Determination of glucosinolates in 19 Chinese medicinal plants with spectrophotometry and high-pressure liquid chromatography. Natural product research, 2010, vol. 24, no. 13, p. 1195-1205.
Li, Jing., Zhou, Beixian., Li, Chufang., Chen, QiaoYan., Wang, Yutao., Li, Zhengtu., Chen, Tingting., Yang, Chunguang., Jiang, Zhihong., Zhong, Nanshan., Yang, Zifeng., Chen, Rongchang. Lariciresinol-4-O-beta-D-glucopyranoside from the root of Isatis indigotica inhibits influenza A virus-induced pro-inflammatory response . Journal of ethnopharmacology, 2015, vol. 174, p. 379-386. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature