Botanical species · safety record

Jatropha curcas

The EFSA Compendium of Botanicals holds 17 constituent measurements and 9 adverse-effect records for Jatropha curcas. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Jatropha curcas L.

17Constituent measurements

9Safety records

8Cited sources

11Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 11 licensed products naming Jatropha curcas as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

New material
Seed
Seed(s)

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Lectins	Seed	—	—	Hemagglutination inhibition (H subtype) test	Resolve DOI
Phorbol esters	Seed	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Phorbol esters	Seed	—	0.73 Milligram/gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Phytic acid	Seed	—	8.55 Percent	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Saponins	Seed	Solvent extraction	27.82 Microgram/gram	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Trypsin inhibitors	Seed	—	7.42 International Unit/gram	Traditional analytical techniques (wet chemical tests)	Resolve DOI
Lectins	Unspecified	—	—	—	No resolvable identifier
Lectins	Unspecified	—	—	—	No resolvable identifier
Lectins	Seed	—	—	—	No resolvable identifier
Phorbol	Seed	—	—	—	No resolvable identifier
Phorbol	Unspecified	—	—	—	No resolvable identifier
Phorbol	Unspecified	—	—	—	No resolvable identifier
Phorbol esters	Seed	Solvent extraction	0.08 Milligram/gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Saponins	Seed	—	—	—	No resolvable identifier
Saponins	Unspecified	—	—	—	No resolvable identifier
Trypsin inhibitors	Seed	—	—	—	No resolvable identifier
Trypsin inhibitors	Unspecified	—	—	—	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Digestive	Digestive	Seed	—	Human (as organism)	Case report	Resolve DOI
Digestive	Digestive	Seed	—	Human (as organism)	Case report	Resolve DOI
Systemic	Digestive	Seed	Solvent extraction	Rat (as animal)	Acute toxicity	Resolve DOI
Digestive	Digestive	Seed	—	Human (as organism)	Acute toxicity	No resolvable identifier
Digestive	Digestive	Unspecified	—	Human (as organism)	Acute toxicity	No resolvable identifier
Digestive	Digestive	Unspecified	—	Human (as organism)	Acute toxicity	No resolvable identifier
Digestive	Digestive	Fruit unspecified	—	—	Case report	No resolvable identifier
Systemic	—	Leaves	Solvent extraction	Rat (as animal)	Subchronic	No resolvable identifier
Systemic	—	Leaves	Solvent extraction	Rat (as animal)	Subchronic	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Saetae, Donlaporn., Suntornsuk, Worapot. Toxic Compound, Anti-Nutritional Factors and Functional Properties of Protein Isolated from Detoxified Jatropha curcas Seed Cake . International journal of molecular sciences, 2011, vol. 12, no. 1, p. 66-77. DOI
Khan, Rehman Ullah., Mehmood, Sultan., Khan, Saad Ullah. Toxic effect of common poisonous plants of district Bannu, Khyber Pakhtunkhwa, Pakistan. Pakistan journal of pharmaceutical sciences, 2018, vol. 31, no. 1, p. 57-67.
Udomsap, Parncheewa., Duangmanee, Thitimapond., Chollacoop, Nuwong. Investigation of the Phorbol Ester Content in High Quality Biodiesel Production Process . 2011 international conference and utility exhibition on power and energy systems: issues & prospects for asia (icue), 2011.
Nakao, Motoyuki., Hasegawa, Go., Yasuhara, Tadashi., Ishihara, Yoko. Degradation of jatropha curcas phorbol esters derived from Jatropha oil cake and their tumor-promoting activity . Ecotoxicology and environmental safety, 2015, vol. 114, p. 357-364. DOI
Sriapha, Charuwan., Tongpoo, Achara., Wongvisavakorn, Sunun., Rittilert, Panee., Trakulsrichai, Satariya., Srisuma, Sahaphume., Wananukul, Winai. PLANT POISONING IN THAILAND: A 10-YEAR ANALYSIS FROM RAMATHIBODI POISON CENTER. Southeast asian journal of tropical medicine and public health, 2015, vol. 46, no. 6, p. 1063-1076.
GANDHI, VM., CHERIAN, KM., MULKY, MJ. TOXICOLOGICAL STUDIES ON RATANJYOT OIL. Food and chemical toxicology, 1995, vol. 33, no. 1, p. 39-42. DOI
See, G.L.L., Perez., Shemei., Tiongson., Diva., Arce, F.V., Jr., Deliman, Y.C. Acute and chronic toxicity studies of Tuba-tuba jatropha curcas L. (1753) leaf extract on albino rats (Rattus norvegicus). International journal of pharmacognosy and phytochemical research, 2016, vol. 8, no. 7, p. 1154-1159.
Kulkarni, M. L., Sreekar, H., Keshavamurthy, K. S., Shenoy, Nivedita. Jatropha curcas - Poisoning. Indian journal of pediatrics, 2005, vol. 72, no. 1, p. 75-76. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature