Botanical species · safety record
Jatropha podagrica
The EFSA Compendium of Botanicals holds 17 constituent measurements and 2 genotoxicity assays for Jatropha podagrica. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Jatropha podagrica Hook.
Regulatory presence
No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.
What the records describe
Constituents measured
- Alkaloids4
- Saponins4
- Tannins4
- Coumarins1
- Diterpene ketones1
- Japodagrin1
- Japodagrone1
- Phorbol esters1
Plant parts
- Roots and other underground parts5
- Leaves4
- Seed4
- Stem3
- stalk3
- Bark1
Preparations
- Solvent extraction17
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Alkaloids | Stem / stalk | Solvent extraction | 0.15 Percent | Phytochemical screening | Resolve DOI |
| Alkaloids | Seed | Solvent extraction | 0.18 Percent | Phytochemical screening | Resolve DOI |
| Alkaloids | Roots and other underground parts | Solvent extraction | 0.26 Percent | Phytochemical screening | Resolve DOI |
| Alkaloids | Leaves | Solvent extraction | 0.33 Percent | Phytochemical screening | Resolve DOI |
| Diterpene ketones | Leaves | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Japodagrin | Roots and other underground parts | Solvent extraction | — | Colorimetry, Spectroscopy (Spectrometry) and Photometry | Resolve DOI |
| Japodagrone | Roots and other underground parts | Solvent extraction | — | Colorimetry, Spectroscopy (Spectrometry) and Photometry | Resolve DOI |
| Saponins | Seed | Solvent extraction | 2.44 Percent | Phytochemical screening | Resolve DOI |
| Saponins | Stem / stalk | Solvent extraction | 2.77 Percent | Phytochemical screening | Resolve DOI |
| Saponins | Leaves | Solvent extraction | 3.15 Percent | Phytochemical screening | Resolve DOI |
| Saponins | Roots and other underground parts | Solvent extraction | 3.25 Percent | Phytochemical screening | Resolve DOI |
| Tannins | Stem / stalk | Solvent extraction | 1.21 Percent | Phytochemical screening | Resolve DOI |
| Tannins | Roots and other underground parts | Solvent extraction | 2.73 Percent | Phytochemical screening | Resolve DOI |
| Tannins | Seed | Solvent extraction | 3.89 Percent | Phytochemical screening | Resolve DOI |
| Tannins | Leaves | Solvent extraction | 6.79 Percent | Phytochemical screening | Resolve DOI |
| Coumarins | Bark | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | No resolvable identifier |
| Phorbol esters | Seed | Solvent extraction | — | Colorimetry, Spectroscopy (Spectrometry) and Photometry | No resolvable identifier |
Genotoxicity testing
Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.
| Outcome | Endpoint | Test | Tested organism | Metabolic activation | Source |
|---|---|---|---|---|---|
| Positive | — | other | Other | — | No resolvable identifier |
| Positive | — | other | House mouse (as animal) | — | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Ilham, M., Yaday, M., Norhanom, A. W. Tumor promoting activity of plants used in Malaysian traditional medicine. Natural product sciences, 1995, p. 31-42.
- Alyelaagbe, Olapeju O., Adesogan, Kayode., Ekundayo, Olusegun., Gloer, James B. Antibacterial diterpenoids from Jatropha podagrica hook. Phytochemistry, 2007, vol. 68, no. 19, p. 2420-2425. DOI
- Adolf, W., Opferkuch, H. J., Hecker, E. Irritant phorbol derivatives from Jatropha species. Phytochemistry (Elsevier), 1984, p. 129-132.
- Rumzhum, N.N., Sohrab, M.H., Al-Mansur, M.A., Rahman, M.S., Hasan, C.M., Rashid, M.A. Secondary metabolites from Jatropha podagrica hook. Journal of physical science, 2012, vol. 23, no. 1, p. 29-37.
- Liu, Wei-Wei., Zhang, Yu., Yuan, Chun-Mao., Yu, Chun., Ding, Jia-Ying., Li, Xiao-Xiao., Hao, Xiao-Jiang., Wang, Qing., Li, Shun-Lin. Japodagricanones A and B, novel diterpenoids from Jatropha podagrica. FITOTERAPIA, 2014, vol. 98, p. 156-159. DOI
- Nwokocha., Blessing, A., Agbagwa, I.O., Okoli, B.E. Comparative phytochemical screening of Jatropha L. Species in the Niger Delta. Research journal of phytochemistry, 2011, vol. 5, no. 2, p. 107-114. DOI
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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