Botanical species · safety record

Jatropha podagrica

The EFSA Compendium of Botanicals holds 17 constituent measurements and 2 genotoxicity assays for Jatropha podagrica. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Jatropha podagrica Hook.

17Constituent measurements
2Safety records
6Cited sources
0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

  • Alkaloids4
  • Saponins4
  • Tannins4
  • Coumarins1
  • Diterpene ketones1
  • Japodagrin1
  • Japodagrone1
  • Phorbol esters1

Plant parts

  • Roots and other underground parts5
  • Leaves4
  • Seed4
  • Stem3
  • stalk3
  • Bark1

Preparations

  • Solvent extraction17

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
AlkaloidsStem / stalkSolvent extraction0.15 PercentPhytochemical screeningResolve DOI
AlkaloidsSeedSolvent extraction0.18 PercentPhytochemical screeningResolve DOI
AlkaloidsLeavesSolvent extraction0.33 PercentPhytochemical screeningResolve DOI
AlkaloidsRoots and other underground partsSolvent extraction0.26 PercentPhytochemical screeningResolve DOI
Diterpene ketonesLeavesSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
JapodagrinRoots and other underground partsSolvent extractionColorimetry, Spectroscopy (Spectrometry) and PhotometryResolve DOI
JapodagroneRoots and other underground partsSolvent extractionColorimetry, Spectroscopy (Spectrometry) and PhotometryResolve DOI
SaponinsRoots and other underground partsSolvent extraction3.25 PercentPhytochemical screeningResolve DOI
SaponinsStem / stalkSolvent extraction2.77 PercentPhytochemical screeningResolve DOI
SaponinsSeedSolvent extraction2.44 PercentPhytochemical screeningResolve DOI
SaponinsLeavesSolvent extraction3.15 PercentPhytochemical screeningResolve DOI
TanninsStem / stalkSolvent extraction1.21 PercentPhytochemical screeningResolve DOI
TanninsSeedSolvent extraction3.89 PercentPhytochemical screeningResolve DOI
TanninsRoots and other underground partsSolvent extraction2.73 PercentPhytochemical screeningResolve DOI
TanninsLeavesSolvent extraction6.79 PercentPhytochemical screeningResolve DOI
CoumarinsBarkSolvent extractionNuclear Magnetic Resonance (NMR)No resolvable identifier
Phorbol estersSeedSolvent extractionColorimetry, Spectroscopy (Spectrometry) and PhotometryNo resolvable identifier

Genotoxicity testing

Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.

OutcomeEndpointTestTested organismMetabolic activationSource
PositiveotherHouse mouse (as animal)No resolvable identifier
PositiveotherOtherNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Ilham, M., Yaday, M., Norhanom, A. W. Tumor promoting activity of plants used in Malaysian traditional medicine. Natural product sciences, 1995, p. 31-42.
  2. Nwokocha., Blessing, A., Agbagwa, I.O., Okoli, B.E. Comparative phytochemical screening of Jatropha L. Species in the Niger Delta. Research journal of phytochemistry, 2011, vol. 5, no. 2, p. 107-114. DOI
  3. Adolf, W., Opferkuch, H. J., Hecker, E. Irritant phorbol derivatives from Jatropha species. Phytochemistry (Elsevier), 1984, p. 129-132.
  4. Alyelaagbe, Olapeju O., Adesogan, Kayode., Ekundayo, Olusegun., Gloer, James B. Antibacterial diterpenoids from Jatropha podagrica hook. Phytochemistry, 2007, vol. 68, no. 19, p. 2420-2425. DOI
  5. Liu, Wei-Wei., Zhang, Yu., Yuan, Chun-Mao., Yu, Chun., Ding, Jia-Ying., Li, Xiao-Xiao., Hao, Xiao-Jiang., Wang, Qing., Li, Shun-Lin. Japodagricanones A and B, novel diterpenoids from Jatropha podagrica. FITOTERAPIA, 2014, vol. 98, p. 156-159. DOI
  6. Rumzhum, N.N., Sohrab, M.H., Al-Mansur, M.A., Rahman, M.S., Hasan, C.M., Rashid, M.A. Secondary metabolites from Jatropha podagrica hook. Journal of physical science, 2012, vol. 23, no. 1, p. 29-37.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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