Botanical species · safety record
Joannesia princeps
The EFSA Compendium of Botanicals holds 15 constituent measurements and 2 adverse-effect records for Joannesia princeps. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Joannesia princeps Vell.
Regulatory presence
No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.
What the records describe
Constituents measured
- Diterpenes2
- 3,3'-bisdemethylpinoresinol1
- 3,4-dihydroxybenzaldehyde1
- 4-hydroxybenzaldehyde1
- Alkaloids1
- Americanol a1
- Corilagin1
- Gallic acid1
- Isoamericanin a1
- Isoamericanol a1
Plant parts
- Seed9
- Leaves4
- Roots and other underground parts4
Preparations
- Solvent extraction16
Effect types
- Digestive1
- Systemic1
Target tissues
- Digestive2
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| 3,3'-bisdemethylpinoresinol | Seed | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| 3,4-dihydroxybenzaldehyde | Roots and other underground parts | Solvent extraction | 0.009 Percent | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| 4-hydroxybenzaldehyde | Leaves | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | Resolve DOI |
| Alkaloids | Seed | Solvent extraction | — | Phytochemical screening | Resolve DOI |
| Americanol a | Seed | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Corilagin | Leaves | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | Resolve DOI |
| Diterpenes | Roots and other underground parts | Solvent extraction | 0.02 Percent | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Diterpenes | Roots and other underground parts | Solvent extraction | 0.01 Percent | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Gallic acid | Leaves | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | Resolve DOI |
| Isoamericanin a | Seed | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Isoamericanol a | Seed | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Joannesialactone | Roots and other underground parts | Solvent extraction | 0.004 Percent | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Lignans | Leaves | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | Resolve DOI |
| Neolignans | Seed | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Steroids | Seed | Solvent extraction | — | Phytochemical screening | Resolve DOI |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Systemic | Digestive | Seed | Solvent extraction | Rat (as animal) | Acute toxicity | Resolve DOI |
| Digestive | Digestive | Seed | — | Human (as organism) | Acute toxicity | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Achenbach, H., Benirschke, G. Joannesialactone and other compounds from Joannesia princeps. Phytochemistry, 1997, vol. 45, no. 1, p. 149-157. DOI
- Waibel, R., Benirschke, G., Benirschke, M., Achenbach, H. Sesquineolignans and other constituents from the seeds of Joannesia princeps . Phytochemistry, 2003, vol. 62, no. 5, p. 805-811. DOI
- Camero, Cesar Munoz., Temraz, Abeer., Braca, Alessandra., De Leo, Marinella. Phytochemical study of Joannesia princeps Vell. (Euphorbiaceae) leaves. Biochemical systematics and ecology, 2017, vol. 70, p. 69-72. DOI
- Araujo, Adriano Cressoni., Guiguer, Elen Landgraf., Barbalho, Sandra Maria., Bueno, Patricia C. S., Lopes, Juliana Agostinho., da Silva, Bruna Ferreira., Girotto, Leticia Cabrini., de Paula, Marina Guirro., Zeber, Paulo Vitor., Goulart, Ricardo de Alvares. Phytochemical Characteristics of Seeds and Its Effects on the Intestinal Motility and Toxicity of Joannesia princeps . Journal of medicinal food, 2016, vol. 19, no. 1, p. 68-72. DOI
- Nishioka, S de A., Escalante, R D. Poisoning by the ingestion of seeds of the fruit of the cotieira (Joannesia princeps). . Sao paulo medical journal = revista paulista de medicina, 1997, vol. 115, no. 1, p. 1366-7.
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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