Botanical species · safety record

Kalanchoe pinnata

The EFSA Compendium of Botanicals holds 12 constituent measurements, 3 adverse-effect records and 1 genotoxicity assay for Kalanchoe pinnata. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Kalanchoe pinnata (Lam.) Pers.

12Constituent measurements

4Safety records

9Cited sources

0Licensed products (Canada)

Also recorded as

Bryophyllum calycinum Salib.
Bryophyllum pinnatum (Lam.) Oken.

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
(+)-pulegone	Leaves	Essential oil	8.7 Percent	GC-FID-MS	Resolve DOI
2-pentylfuran	Leaves	Essential oil	2.1 Percent	GC-FID-MS	Resolve DOI
Alkaloids	Leaves	Solvent extraction	—	Phytochemical screening	Resolve DOI
Bufadienolides	Leaves	Solvent extraction	—	UV/VIS spectroscopy (photometry)	Resolve DOI
Bufadienolides	Leaves	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Nonanal	Leaves	Essential oil	17.3 Percent	GC-FID-MS	Resolve DOI
Saponins	Leaves	Solvent extraction	—	Phytochemical screening	Resolve DOI
Tannins	Leaves	Solvent extraction	—	Phytochemical screening	Resolve DOI
Alkaloids	Leaves	Solvent extraction	243.3 Milligram/100 gram	Phytochemical screening	No resolvable identifier
Alkaloids	Leaves	Solvent extraction	1.48 Milligram/100 gram	Phytochemical screening	No resolvable identifier
Saponins	Leaves	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Saponins	Leaves	Solvent extraction	458.2 Milligram/100 gram	Phytochemical screening	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Neurotoxicity	Neurologic: central nervous system	Leaves	Solvent extraction	House mouse (as animal)	Acute toxicity	Resolve DOI
Neurotoxicity	Neurologic: central nervous system	Leaves	Solvent extraction	House mouse (as animal)	Acute toxicity	Resolve DOI
Systemic	Respiratory	Aerial part of plants	Fresh	Cattle (as animal)	Case report	Resolve DOI

Genotoxicity testing

Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.

Outcome	Endpoint	Test	Tested organism	Metabolic activation	Source
Positive	chromosome aberration	chromosome aberration assay	Rat (as animal)	Not applicable	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

REPPAS, GP. BRYOPHYLLUM PINNATUM POISONING OF CATTLE. Australian veterinary journal, 1995, vol. 72, no. 11, p. 425-427. DOI
Sowemimo, A. A., Fakoya, F. A., Awopetu, I., Omobuwajo, O. R., Adesanya, S. A. Toxicity and mutagenic activity of some selected Nigerian plants. Journal of ethnopharmacology, 2007, vol. 113, no. 3, p. 427-432. DOI
Yemitan, OK., Salahdeen, HM. Neurosedative and muscle relaxant activities of aqueous extract of Bryophyllum pinnatum . Fitoterapia, 2005, vol. 76, no. 2, p. 187-193. DOI
Biswas, S.K., Chowdhury, A., Raihan, S.Z., Muhit, M.A., Akbar, M.A., Mowla, R. Phytochemical investigation with assessment of cytotoxicity and antibacterial activities of chloroform extract of the leaves of kalanchoe pinnata. American journal of plant physiology, 2012, vol. 7, no. 1, p. 41-46. DOI
Okwu, DE., Josiah, C. Evaluation of the chemical composition of two Nigerian medicinal plants. African journal of biotechnology, 2006, vol. 5, no. 4, p. 357-361.
Afolabi, F., Afolabi, O. J. Phytochemical constituents of some medicinal plants in South West, Nigeria. Iosr journal of applied chemistry, 2013, vol. 4, no. 1), 76-7, p. 3 pp.
Aboaba, Sherifat Adeyinka., Igumoye, Hezekiah., Flamini, Guido. Chemical composition of the leaves and stem bark of Sterculia tragacantha, Anthocleista vogelii and leaves of Bryophyllum pinnatum . Journal of essential oil research, 2017, vol. 29, no. 1, p. 85-92. DOI
Supratman, U., Fujita, T., Akiyama, K., Hayashi, H., Murakami, A., Sakai, H., Koshimizu, K., Ohigashi, H. Anti-tumor promoting activity of bufadienolides from Kalanchoe pinnata and K. daigremontiana X tubiflora . Bioscience biotechnology and biochemistry, 2001, vol. 65, no. 4, p. 947-949. DOI
Supratman, U., Fujita, T., Akiyama, K., Hayashi, H. New insecticidal bufadienolide, bryophyllin C, from Kalanchoe pinnata. Bioscience biotechnology and biochemistry, 2000, vol. 64, no. 6, p. 1310-1312. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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