Botanical species · safety record

Kalmia latifolia

The EFSA Compendium of Botanicals holds 4 constituent measurements and 1 adverse-effect record for Kalmia latifolia. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Kalmia latifolia L.

4Constituent measurements
1Safety records
3Cited sources
31Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 31 licensed products naming Kalmia latifolia as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

  • Fresh leaf
  • Fresh leaves
  • Leaf
  • Leaf gel
  • Leaf/Leaves
  • Leaves

What the records describe

Constituents measured

  • Diterpenes2
  • Grayanotoxins2

Plant parts

  • Leaves3
  • Aerial part of plants2

Preparations

  • Solvent extraction3
  • Fresh1
  • Sap1

Effect types

  • Systemic1

Target tissues

  • Neurologic1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
DiterpenesLeavesSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
DiterpenesLeavesSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
GrayanotoxinsAerial part of plantsSapNuclear Magnetic Resonance (NMR)Resolve DOI
GrayanotoxinsLeavesSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
SystemicNeurologicAerial part of plantsFreshDog (as animal)Case reportResolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. MANCINI, SD., EDWARDS, JM. CYTOTOXIC PRINCIPLES FROM THE SAP OF KALMIA-LATIFOLIA. Journal of natural products, 1979, vol. 42, no. 5, p. 483-488. DOI
  2. ELNAGGAR, SF., DOSKOTCH, RW., ODELL, TM., GIRARD, L. ANTIFEEDANT DITERPENES FOR THE GYPSY-MOTH LARVAE FROM KALMIA-LATIFOLIA - ISOLATION AND CHARACTERIZATION OF 10 GRAYANOIDS . Journal of natural products, 1980, vol. 43, no. 5, p. 617-631. DOI
  3. Manhart, Ingrid O., DeClementi, Camille., Guenther, Christine L. Mountain laurel toxicosis in a dog. Journal of veterinary emergency and critical care, 2013, vol. 23, no. 1, p. 77-81. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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