Botanical species · safety record

Khaya senegalensis

The EFSA Compendium of Botanicals holds 7 constituent measurements and 6 adverse-effect records for Khaya senegalensis. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Khaya senegalensis (Desv.) A.Juss.

7Constituent measurements

6Safety records

7Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Alkaloids	Bark	Solvent extraction	—	Phytochemical screening	Resolve DOI
Cardiac glycosides	Bark	Solvent extraction	—	Phytochemical screening	Resolve DOI
Tannins	Bark	Solvent extraction	—	Phytochemical screening	Resolve DOI
Anthracene derivatives	Bark	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Cyanogenic glycosides	Bark	Drying (dehydration)	—	Phytochemical screening	No resolvable identifier
Saponins	Bark	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Tannins	Bark	Solvent extraction	—	Phytochemical screening	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Hepatotoxicity	Liver	Bark	Solvent extraction	Rat (as animal)	Short-term toxicity	Resolve DOI
Nephrotoxicity	Urogenital: kidneys	Bark	Solvent extraction	Rat (as animal)	Short-term toxicity	Resolve DOI
Nephrotoxicity	Urogenital: kidneys	Bark	Solvent extraction	Rat (as animal)	Short-term toxicity	Resolve DOI
Digestive	Digestive	Bark	Drying (dehydration)	Human (as organism)	Case report	No resolvable identifier
Hepatotoxicity	Liver	Leaves	Drying (dehydration)	Rabbit (as animal)	Short-term toxicity	No resolvable identifier
Nephrotoxicity	Urogenital: kidneys	Leaves	Drying (dehydration)	Rabbit (as animal)	Short-term toxicity	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Nwosu, C.O., Yahayah, K., Igbokwe, I.O. Toxicity and anticoccidial efficacy of some plants used in the traditional treatment of avian coccidiosis in semi-arid northeastern Nigeria. Research journal of parasitology, 2011, vol. 6, no. 1, p. 18-30. DOI
Agossou, Esse., Ahokpe, Melanie., Behanzin, Justin., Takin, Marcellin., Yessoufou, Ganiou., Zohoun, Loica., Baba-Moussa, Lamine., Sezan, Alphonse. Effect of the ethanolic extract of Khaya senegalensis on some biochemical parameters on rabbit's in glucose overload condition. American journal of plant sciences, 2015, p. 240-248.
Adebayo, JO., Yakubu, MT., Egwim, EC., Owoyele, VB., Enaibe, BU. Effect of ethanolic extract of Khaya senegalensis on some biochemical parameters of rat kidney. JOURNAL OF ETHNOPHARMACOLOGY, 2003, vol. 88, no. 1, p. 69-72. DOI
Kolawole, S.O., Kolawole, O.T., Akanji, M.A. Effects of aqueous extract of Khaya senegalensis stem bark on biochemical and hematological parameters in rats. Journal of Pharmacology and Toxicology, 2011, vol. 6, no. 6, p. 602-607. DOI
Tchacondo, Tchadjobo., Karou, Simplice D., Batawila, Komlan., Agban, Amegninou., Ouro-Bang'na, Kawiwou., Anani, Kokou T., Gbeassor, Mensavi., de Souza, Comlan. HERBAL REMEDIES AND THEIR ADVERSE EFFECTS IN TEM TRIBE TRADITIONAL MEDICINE IN TOGO . African journal of traditional complementary and alternative medicines, 2011, vol. 8, no. 1, p. 45-60.
Abdel-Wareth, A. A. A., Hammad, Seddik., Ahmed, Hassan. EFFECTS OF KHAYA SENEGALENSIS LEAVES ON PERFORMANCE, CARCASS TRAITS, HEMATOLOGICAL AND BIOCHEMICAL PARAMETERS IN RABBITS. EXCLI JOURNAL, 2014, vol. 13, p. 502-512.
Lal�y�, O.A.F., Ahissou, H., Olounlad�, A.P., Azando, V.B.E., Dansou, C., Lal�y�, A. Phytochemical screening and evaluation of antihyperglycemic, antiradical and acute oral toxicty activities of aqueous extract of stem bark of khaya senegalensis A. Juss (meliaceae) from Benin. International journal of pharmacognosy and phytochemical research, 2015, vol. 7, no. 3, p. 513-518.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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