Botanical species · safety record

Laburnum anagyroides

The EFSA Compendium of Botanicals holds 7 constituent measurements and 2 adverse-effect records for Laburnum anagyroides. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Laburnum anagyroides Medik.

7Constituent measurements

2Safety records

4Cited sources

4Licensed products (Canada)

Also recorded as

Laburnum vulgare J.Presl.
Cytisus laburnum L.

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 4 licensed products naming Laburnum anagyroides as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

Flowering twigs

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Cytisine	Seed	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
N-methylcytisine	Seed	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Quinolizidine alkaloids	Seed	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Quinolizidine alkaloids	Seed	—	2 Percent	Unspecified	Resolve DOI
Quinolizidine alkaloids	Leaves	—	≤ 0.4 Percent	Unspecified	Resolve DOI
Quinolizidine alkaloids	Leaves	—	≥ 0.3 Percent	Unspecified	Resolve DOI
Quinolizidine alkaloids	Flower	—	0.9 Percent	Unspecified	Resolve DOI

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Digestive	Digestive	Seed	Fresh	Human (as organism)	Case report	Resolve DOI
Systemic	Lung	Aerial part of plants	Solvent extraction	Human (as organism)	Case report	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Musshoff, F., Madea, B. Fatal cytisine intoxication and analysis of biological samples with LC-MS/MS . Forensic science international, 2009, vol. 186, no. 1-3, p. E1-E4. DOI
Gray, A.I., Henman, M.C., Meegan, C.J. (-)-N.-(3-OXOBUTYL)-CYTISINE, A TOXIC ALKALOID FROM LABURNUM ANAGYROIDES. Journal of pharmacy and pharmacology, 1981, vol. 33, no. 1 S, p. 95P-95P. DOI
Schep, Leo J., Slaughter, Robin J., Beasley, D. Michael G. Nicotinic plant poisoning. Clinical toxicology, 2009, vol. 47, no. 8, p. 771-781. DOI
Vichova, P., Jahodar, L. Plant poisonings in children in the Czech Republic, 1996-2001. Human and experimental toxicology, 2003, vol. 22, no. 9, p. 467-472. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature