Botanical species · safety record
Lappula squarrosa
The EFSA Compendium of Botanicals holds 20 constituent measurements for Lappula squarrosa. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Lappula squarrosa (Retz.) Dumort.
Regulatory presence
No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.
What the records describe
Constituents measured
- Intermedine5
- Lycopsamine5
- Supinine4
- Amabiline3
- Pyrrolizidine alkaloids3
Plant parts
- Roots and other underground parts7
- Leaves6
- Flower4
- Seed3
Preparations
- Solvent extraction19
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Amabiline | Flower | Solvent extraction | ≤ 0.67 Milligram/gram | GC-MS | Resolve DOI |
| Amabiline | Leaves | Solvent extraction | ≤ 0.1 Milligram/gram | GC-MS | Resolve DOI |
| Amabiline | Roots and other underground parts | Solvent extraction | ≤ 2.53 Milligram/gram | GC-MS | Resolve DOI |
| Intermedine | Leaves | Solvent extraction | ≤ 0.09 Milligram/gram | GC-MS | Resolve DOI |
| Intermedine | Roots and other underground parts | Solvent extraction | ≤ 3.39 Milligram/gram | GC-MS | Resolve DOI |
| Intermedine | Roots and other underground parts | Solvent extraction | ≥ 0.12 Milligram/gram | GC-MS | Resolve DOI |
| Intermedine | Flower | Solvent extraction | ≤ 2.28 Milligram/gram | GC-MS | Resolve DOI |
| Intermedine | Leaves | Solvent extraction | ≥ 0.02 Milligram/gram | GC-MS | Resolve DOI |
| Lycopsamine | Flower | Solvent extraction | ≤ 3.59 Milligram/gram | GC-MS | Resolve DOI |
| Lycopsamine | Roots and other underground parts | Solvent extraction | ≤ 2.67 Milligram/gram | GC-MS | Resolve DOI |
| Lycopsamine | Roots and other underground parts | Solvent extraction | ≥ 0.13 Milligram/gram | GC-MS | Resolve DOI |
| Lycopsamine | Leaves | Solvent extraction | ≤ 0.13 Milligram/gram | GC-MS | Resolve DOI |
| Lycopsamine | Leaves | Solvent extraction | ≥ 0.02 Milligram/gram | GC-MS | Resolve DOI |
| Pyrrolizidine alkaloids | Seed | Solvent extraction | ≤ 10.36 Microgram/gram | HPLC with standard detection methods | Resolve DOI |
| Pyrrolizidine alkaloids | Seed | Solvent extraction | ≥ 2.88 Microgram/gram | HPLC with standard detection methods | Resolve DOI |
| Pyrrolizidine alkaloids | Seed | — | 29 Microgram/kilogram | HPLC with standard detection methods | Resolve DOI |
| Supinine | Flower | Solvent extraction | ≤ 0.5 Milligram/gram | GC-MS | Resolve DOI |
| Supinine | Roots and other underground parts | Solvent extraction | ≥ 0.09 Milligram/gram | GC-MS | Resolve DOI |
| Supinine | Leaves | Solvent extraction | ≤ 0.15 Milligram/gram | GC-MS | Resolve DOI |
| Supinine | Roots and other underground parts | Solvent extraction | ≤ 2.61 Milligram/gram | GC-MS | Resolve DOI |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Letsyo E., Jerz G., Winterhalter P., Horn G., Beuerle T. Survey of pyrrolizidine alkaloids in seven varieties of Lappula squarrosa: Analternative source of heart-healthy vegetable oil.. Phytochemical analysis : PCA, 2016, vol. 27, no. 2, p. 133-9. DOI
- Cramer, Luise., Fleck, Gunther., Horn, Gert., Beuerle, Till. Process Development of Lappula squarrosa Oil Refinement: Monitoring of Pyrrolizidine Alkaloids in Boraginaceae Seed Oils. JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 2014, vol. 91, no. 5, p. 721-731. DOI
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
Continue
Europe PMC
Every record indexed for this species, resolvable and re-runnable.
All speciesSubstance index
Search and browse every species this world holds under source and hash.
Before anything elseSafety Centre
Interactions, contraindications and the escalation boundary this world does not cross.
In its own termsTraditions
How the living traditions approach preparation, use and context.