Botanical species · safety record

Lappula squarrosa

The EFSA Compendium of Botanicals holds 20 constituent measurements for Lappula squarrosa. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Lappula squarrosa (Retz.) Dumort.

20Constituent measurements
0Safety records
2Cited sources
0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

  • Intermedine5
  • Lycopsamine5
  • Supinine4
  • Amabiline3
  • Pyrrolizidine alkaloids3

Plant parts

  • Roots and other underground parts7
  • Leaves6
  • Flower4
  • Seed3

Preparations

  • Solvent extraction19

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
AmabilineFlowerSolvent extraction≤ 0.67 Milligram/gramGC-MSResolve DOI
AmabilineLeavesSolvent extraction≤ 0.1 Milligram/gramGC-MSResolve DOI
AmabilineRoots and other underground partsSolvent extraction≤ 2.53 Milligram/gramGC-MSResolve DOI
IntermedineLeavesSolvent extraction≤ 0.09 Milligram/gramGC-MSResolve DOI
IntermedineRoots and other underground partsSolvent extraction≤ 3.39 Milligram/gramGC-MSResolve DOI
IntermedineRoots and other underground partsSolvent extraction≥ 0.12 Milligram/gramGC-MSResolve DOI
IntermedineFlowerSolvent extraction≤ 2.28 Milligram/gramGC-MSResolve DOI
IntermedineLeavesSolvent extraction≥ 0.02 Milligram/gramGC-MSResolve DOI
LycopsamineFlowerSolvent extraction≤ 3.59 Milligram/gramGC-MSResolve DOI
LycopsamineRoots and other underground partsSolvent extraction≤ 2.67 Milligram/gramGC-MSResolve DOI
LycopsamineRoots and other underground partsSolvent extraction≥ 0.13 Milligram/gramGC-MSResolve DOI
LycopsamineLeavesSolvent extraction≤ 0.13 Milligram/gramGC-MSResolve DOI
LycopsamineLeavesSolvent extraction≥ 0.02 Milligram/gramGC-MSResolve DOI
Pyrrolizidine alkaloidsSeedSolvent extraction≤ 10.36 Microgram/gramHPLC with standard detection methodsResolve DOI
Pyrrolizidine alkaloidsSeedSolvent extraction≥ 2.88 Microgram/gramHPLC with standard detection methodsResolve DOI
Pyrrolizidine alkaloidsSeed29 Microgram/kilogramHPLC with standard detection methodsResolve DOI
SupinineFlowerSolvent extraction≤ 0.5 Milligram/gramGC-MSResolve DOI
SupinineRoots and other underground partsSolvent extraction≥ 0.09 Milligram/gramGC-MSResolve DOI
SupinineLeavesSolvent extraction≤ 0.15 Milligram/gramGC-MSResolve DOI
SupinineRoots and other underground partsSolvent extraction≤ 2.61 Milligram/gramGC-MSResolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Letsyo E., Jerz G., Winterhalter P., Horn G., Beuerle T. Survey of pyrrolizidine alkaloids in seven varieties of Lappula squarrosa: Analternative source of heart-healthy vegetable oil.. Phytochemical analysis : PCA, 2016, vol. 27, no. 2, p. 133-9. DOI
  2. Cramer, Luise., Fleck, Gunther., Horn, Gert., Beuerle, Till. Process Development of Lappula squarrosa Oil Refinement: Monitoring of Pyrrolizidine Alkaloids in Boraginaceae Seed Oils. JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 2014, vol. 91, no. 5, p. 721-731. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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