Botanical species · safety record

Lathyrus sativus

The EFSA Compendium of Botanicals holds 12 constituent measurements and 3 adverse-effect records for Lathyrus sativus. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Lathyrus sativus L.

12Constituent measurements

3Safety records

5Cited sources

16Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 16 licensed products naming Lathyrus sativus as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

Grain(s)
Seed
Seed(s)
Tincture of the seeds

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Beta-n-oxalyl-alpha,beta-diaminopropionic acid (beta-odap)	Seed	—	≤ 1.5 Percent	Unspecified	Resolve DOI
Beta-n-oxalyl-alpha,beta-diaminopropionic acid (beta-odap)	Seed	—	≥ 0.04 Percent	Unspecified	Resolve DOI
Beta-n-oxalyl-alpha,beta-diaminopropionic acid (beta-odap)	Seed	Solvent extraction	≤ 0.45 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Beta-n-oxalyl-alpha,beta-diaminopropionic acid (beta-odap)	Seed	Solvent extraction	≥ 0.3 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Beta-n-oxalyl-alpha,beta-diaminopropionic acid (beta-odap)	Seed	Powder	≤ 1.33 Percent	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Beta-n-oxalyl-alpha,beta-diaminopropionic acid (beta-odap)	Seed	Powder	≥ 1.23 Percent	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Phytic acid	Seed	Powder	≤ 6.75 Percent	—	Resolve DOI
Phytic acid	Seed	—	≥ 0.49 Percent	Unspecified	Resolve DOI
Phytic acid	Seed	—	≤ 1.09 Percent	Unspecified	Resolve DOI
Phytic acid	Seed	Powder	≥ 6.29 Percent	—	Resolve DOI
Trypsin inhibitors	Seed	Powder	≥ 30.49 Percent	—	Resolve DOI
Trypsin inhibitors	Seed	Powder	≤ 32.35 Percent	—	Resolve DOI

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Neurotoxicity	Muscle, skeletal	Seed	Solvent extraction	Rhesus monkey (as animal)	Subchronic	Resolve DOI
Neurotoxicity	Muscle, skeletal	Seed	Solvent extraction	Rhesus monkey (as animal)	Subchronic	Resolve DOI
Musclo-skeletal	Muscle, skeletal	Seed	—	Human (as organism)	Case report	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Hanbury, CD., White, CL., Mullan, BP., Siddique, KHM. A review of the potential of Lathyrus sativus L. and L. cicera L. grain for use as animal feed . Animal feed science and technology, 2000, vol. 87, no. 1-2, p. 1-27. DOI
Ramachandran, S., Ray, A.K. Effect of different processing techniques on the nutritive value of grass pea, lathyrus sativus l., seed meal in compound diets for indian major carp rohu, labeo rohita (hamilton), fingerlings. Archives of polish fisheries, 2008, vol. 16, no. 2, p. 189-202. DOI
Xing, GM., Wang, F., Cui, KR., Li, ZX. Assay of neurotoxin beta-ODAP and non-protein amino acids in Lathyrus sativus by high-performance liquid chromatography with dansylation . Analytical letters, 2001, vol. 34, no. 15, p. 2649-2657. DOI
Spencer, PS. Food toxins, AMPA receptors, and motor neuron diseases. Drug metabolism reviews, 1999, vol. 31, no. 3, p. 561-587. DOI
Cohn, D F., Streifler, M. Intoxication by the chickling pea (Lathyrus sativus): nervous system and skeletal findings. . Archives of toxicology. supplement. = archiv fur toxikologie. supplement, 1983, vol. 6, p. 190-3.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature